After interim analysis CureVac defends its vaccine

Status: 06/18/2021 10:19 a.m.

Although an interim analysis of the CureVac vaccine only showed an effectiveness of 47 percent, company boss Haas does not want to know anything about a failure. He is hoping for further tests so that the vaccine will be ready for the market after all. The negative news for the Tübingen company CureVac continues. At first, the company lagged behind the competition in developing its corona vaccine. Then the company went late to the crucial phase 3 to test its vaccine – at that time there were already several variants of the coronavirus. The next bad news followed yesterday: CureVac announced in a mandatory stock market announcement that, according to an interim analysis, its corona vaccine had a preliminary effectiveness of 47 percent against Covid 19 disease “of any severity” have. The value is significantly higher for the other preparations approved in the EU.

“Wild type hardly plays a role anymore”

Company boss Franz-Werner Haas has now gone on the offensive. He defended the company’s corona vaccine against the dpa news agency. No other vaccine has been tested on so many virus variants, he said.

“In fact, it is actually not correct to compare the number of the provisional effectiveness of our corona vaccine and the numbers of the effectiveness of other vaccines”said Haas. The study on the corona vaccine candidate CVnCov contained 29 virus variants. The original virus, the wild type, hardly plays a role anymore. “The efficacy figures for the other vaccines would probably look different if their studies had been carried out at a later date.”

Degree in three weeks

The Tübingen-based company would like to complete the analysis of the data from the final study phase in the next two to three weeks. Haas was convinced that the effectiveness of the vaccine would change again. As soon as this has been completed, CureVac will advise the EMA as to whether further data is required.

The company remains convinced that it will bring its vaccine to approval. According to Haas, even a possibly relatively low effectiveness should not stand in the way. “In view of the pandemic, it can only be said: If there is an effective vaccine, it should also be used.” Haas also referred to the numerous developing countries in which little or no corona vaccines are currently available. The scientific director of the vaccine study at CureVac, Peter Kremsner, believes that it will certainly be possible to make the vaccine operational. In an interview with the BR he said: “That will work for sure. From my point of view, this will not be possible in the next few weeks. But it will be possible to prepare the vaccine so that it can be very effective.”

“It was a noble cause”

The SPD health expert Karl Lauterbach estimates that the setback when entering the market will contribute to the vaccination campaign losing pace for two to three weeks. The promise of the federal government to make a vaccination offer to all adults by the end of the summer is not at risk. “We will reach herd immunity in mid-September”said Lauterbach in the daily topics .

Lauterbach pointed out that the CureVac serum is the “noble” I wanted to be a cheap and very effective vaccine. It would have been predestined for poorer countries. The EU had promised 400 million doses of CureVac to poorer countries. Lauterbach assessed it as a tragedy that this delivery has now been canceled.

No withdrawal of the investor

The announcement of the preliminary effectiveness had caused a drastic plunge in the stock exchange price of CureVac. Investor Dietmar Hopp still believes in the company. He will definitely stay as an investor, he said “Munich Mercury”. He is a firm believer in the company.

The federal government is also holding on to its stake in CureVac, as the Ministry of Economic Affairs said. Last year, he entered CureVac through the KfW development bank with 300 million euros and, according to KfW, holds a share of 16 percent. The federal government has no influence on the operational business, explained the ministry spokeswoman

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According to the gardeners, although the price is as cheap as vegetables, plum rice is still unprecedented. Traders come to buy a little, ripe red plums on the tree, people do not bother to harvest. Mr. Nguyen Van Trong – a rice plum growing household in Chieng Co commune (Son La) – shared, his family has been growing plums for decades, but never fell in such a tragic situation. With the amount of up to 2,000 rice plums, his family is estimated to have around 25 tons of plums every year. The rice plum in Son La is in a flourishing harvest, but the price has dropped sharply. Photo: Nhat Thanh In previous years, since the beginning of the March crop, the traders’ car ran loudly to the buying garden. At one point, the price of plum rice at the beginning of the season was up to 70,000-80,000 VND / kg, but the quantity was not much. This year, the atmosphere is quiet, plum rice is cheap, partly due to the good season, and the output pumpkins, so the selling price at the garden is record low. Mr. Trong said that last year, he sold beautiful big fruits for 18,000 VND / kg. This year, the price of plum drops to 10,000 VND / kg, the cheapest bucket is only 1,500-2,000 VND / kg. Currently, he wholesales each bag from 50-52kg, the average price is 5,000 VND / kg. Although the price is so cheap, Mr. Trong reflects that the number of plums sold this year has decreased significantly. As every year, on average, he dumped to the provinces about 5 tons / day, now he only sells about 3 tons / day. In addition to the amount of fruits collected from his home garden, he also collects from local people. Gardeners said that this type of plums eat green better than ripe. Photo: Nhat Thanh In the year when traders were slow to purchase, plums in the garden began to ripen red. Photo: Nhat Thanh In the same situation, Ms. Nguyen Quynh – another rice plum growing household in Son La – lamented, with the price as low as giving, has not been able to buy a cup of iced tea in a year. Last year, the cheapest goods she also sold was 8,000-9,000 VND / kg, beautiful goods cost 15,000-20,000 VND / kg. Now, the plum is small, mixed green, she sells for 120,000 VND / bag (50-52kg), only about 2,300 VND / kg; selected products with large fruit prices are only 3,500-6,000 VND / kg. Even plums fell at 1,000 VND / kg, there was no buyer. “The selling price is a few thousand dong, which is enough to compensate for the rent of the pickers, the money for canning, packing is all, not to mention the fertilizer fee, the effort is considered to give away. Now if you can’t sell it, you will lose a lot, ”she said, boredly. Ms. Quynh said, the plum rice season starts from March and lasts until May is over, then comes the plum season. However, this year, due to the fact that the goods cannot be sold for sale, there is no clue to buy, the sales volume is quite slow, many trees in her garden have become red and red. Plum prices are currently down to a few thousand VND / kg still meager. Photo: Nhat Thanh “This plum type, when the fruit is still green, can be sold when it is crispy and sour, only to be thrown away if it is ripe,” she said. On average, each tree gives about 30kg of fruit / crop. Her family’s crop this year is about 12 tons, but the amount of ripe fruit removed is 4-5 tons, the rest has not been sold much. Ms. Tran Hai Yen – the focal point selling plum rice in Trieu Khuc (Thanh Xuan, Hanoi), also commented that she has been selling Son La plums for 3-4 years now, seeing this is also a rare year for plum prices to drop so low. . Currently, retail plums are 20,000-25,000 VND / kg, wholesale from 5kg is priced at 15,000 VND / kg. In previous years, the price of plums ranged from 30,000 to 60,000 VND / kg, sometimes up to 90,000 VND / kg. Cheap, one day she can sell 50-60kg because customers buy more food. On the internet market, many clues are selling this plum with a retail price of only 10,000-13,000 VND / kg, even some places sell 5kg combo for 35,000 VND, not retail, attracting a lot of women. buy.

Ingredients for mixed jellyfish salad Jellyfish
Carrot, cucumber (or banana flower, green mango), onion, bean sprouts.
Basil, marjoram, coriander.
Roasted peanuts, white sesame Lemon, vinegar, sugar, garlic, chili, lime leaf, lemongrass, ginger, cooking oil, salt … The ingredients for making mixed jellyfish dummies. How to make mixed jellyfish salad Jellyfish wash thoroughly with lemon / vinegar to remove fishy smell, dirty oil, drain, cut into bite-sized pieces. Rinse thoroughly with warm water mixed with ginger, then squeeze the jellyfish dry.
Washed carrots, onions, peeled, shredded / shredded. Particularly, cucumbers need to remove the intestines, leave the skin, sliced ​​just right to keep the crunch. Soak this ingredient with vinegar for 10 minutes and then take out and drain. Wash the materials. If you mix jellyfish salad with banana flower, banana flower after slicing, need to soak in dilute salt water to remove plastic. Shredded green mangoes do the same. Finished soaking the ingredients, take out, squeeze lightly.

Wash bean sprouts and soak them with dilute salt water, take them out to drain. All kinds are fragrant washed and soaked with dilute salt water, then picked out to drain, cut into bite size.

Mixed mixed jellyfish salad: 2 teaspoons of filtered water + 2 teaspoons of vinegar + 1 teaspoon of lemon juice + 1 teaspoon of sugar + 1.5 teaspoons of cooking oil + 1 teaspoon of salt. Dissolve the mixture and add chili, minced garlic.
Put the jellyfish, vegetables, water, mix in a large bowl and mix well, leave for about 20-30 minutes for the jellyfish salad to infuse spices. Make mixed jellyfish salad on a large plate, sprinkle with coriander, roasted peanuts, white sesame on top. The sweet and sour mixed water makes the jellyfish mixed salad more bold. Delicious dishes every day: Mixed jellyfish salad.