Manufacturers deliver less Vaccination campaign could stall

Status: 16.06.2021 2:47 p.m. In Germany there will be fewer BioNTech cans available next month. Johnson & Johnson is also delivering less than planned. The German vaccination campaign could suffer a setback as a result. The vaccine manufacturer BioNTech will deliver significantly less vaccine to Germany in July than in June. Instead of 5.7 million cans for the last week of June, only 3.2 million cans are planned for the first week of July (KW 27). But there could be no question of a surprising cut, said a spokesman for the Federal Ministry of Health. Rather, BioNTech preferred deliveries in June that were actually intended for later. It was always clear that the delivery volume of the Mainz manufacturer in the third quarter would be around 40.2 million vaccination doses lower than the around 50 million in the second quarter. So far there has only been a clear delivery promise for the first week of July with 3.235 million cans. After that, around 3.3 million doses per week can be expected. That was also communicated to the federal states. SPD health expert Karl Lauterbach therefore warns of a setback for the vaccination campaign: “If the BioNTech deliveries fall so sharply, it will be difficult to demonstrate herd immunity before mid-September,” he told the “Spiegel”. At the same time, it is shown that the delta variant is highly infectious and sometimes causes severe disease. “That’s scary,” said Lauterbach.

06/02/2021

6.5 million fewer doses from Johnson & Johnson

The US pharmaceutical company Johnson & Johnson (J&J) will also deliver significantly fewer vaccine doses than planned. The European Commission expects that J&J will not be able to meet its delivery targets to the EU for the second quarter. The reason for this is a decision by the European Medicines Agency (EMA), according to which 17 million doses of the vaccine cannot be used in the EU for safety reasons after cases of contamination have occurred in a US plant. The group will therefore probably not reach its delivery target of 55 million cans by the end of June, says a commission spokesman. So far, only around twelve million cans have been delivered. The Federal Ministry of Health estimates that J&J will be able to deliver around 6.5 million fewer doses to Germany than planned by the end of June because of the breakdown. “That is unfortunate, because every vaccine counts,” said a spokeswoman. The ministry expects the missing quantity to be replenished in July.

June 16, 2021

Waiting for Sputnik and Curevac

The Germans will probably have to wait even longer for the Russian vaccine Sputnik V, because, according to government circles, approval will be postponed “probably to September, maybe even to the end of the year”. The reason is that the Russian manufacturer has not yet submitted the necessary clinical trial data to the European Medicines Agency (EMA), the news agency Reuters learned from government circles. The clinical dossier was supposed to be available by June 10th. The Russian state fund RDIF, which sells Sputnik V, described the information as incorrect. All the necessary data on the clinical studies have been submitted and received positive comments. Initially, no comments were received from the EMA. The vaccine from Curevac is also not yet available. The vaccine from the Tübingen company, once praised as a bearer of hope, is still not approved. The Federal Ministry of Health has therefore canceled the delivery of 1.4 million vaccine doses originally planned for the current second quarter. According to health expert Lauterbach, the delay in approval could indicate that the effectiveness of the Curevac vaccine is not looking good.

06/07/2021

Moderna delivers a little more

Meanwhile, there are increasing complaints about the shortage of vaccines – from company doctors, general practitioners and some vaccination centers. The calls from some prime ministers for more vaccine also persist – while millions of Germans are still waiting for an initial vaccination. There is positive news from Moderna: The US manufacturer will increase its delivery volume compared to June, from 622,000 to 733,000 cans per week. In addition, Schleswig-Holstein is giving part of the AstraZeneca vaccine provided by Denmark to Hamburg. Thanks to the delivery, at least 8,000 new appointments can be made in the vaccination center in the megacity since today. The neighboring state does not manage to use the cans from Danish stock in time before the expiry date at the end of June.

background June 15, 2021

South Africa throws away 2 million doses of COVID-19 vaccine due to contamination incident. Photo: Reuters According to RT (Russia) news agency (Russia), the South African Health Products Administration (SAHPRA) has decided not to deploy vaccination for 2 million doses of Johnson & Johnson vaccine being stored at a facility in the city of Gqeberha. , as the raw materials for their production were affected by a contamination incident at the factory in Baltimore (USA). The decision comes after the US Food and Drug Administration (FDA) said that millions of doses of vaccine produced at Johnson & Johnson’s Emergent BioSolutions facility in the US city of Baltimore were not suitable for use in the United States. use. “Based on what has been announced by the FDA, batches of vaccines being stored in our Gqeberha have been affected. The batches of these vaccines correspond to about 2 million doses,” South Africa’s Acting Health Minister Mmamoloko Kubayi-Ngubane said on June 13. These doses of the vaccine have not and will not be used to immunize South Africans, she added. SAHPRA chief executive, Dr Boitumelo Semete, also confirmed the batch of vaccines “cannot be widely distributed.” Meanwhile, South Africa’s health watchdog said in a statement that a new batch of about 300,000 doses of Johnson & Johnson’s COVID-19 vaccine has been approved by the FDA and will be shipped to South Africa at a later date. some point. The agency did not disclose the exact date the shipments arrived. However, Mr. Semete acknowledged that the problem with Johnson & Johnson’s vaccine had a significant negative impact on South Africa’s vaccine deployment strategy. As of June 13, South Africa, the country hardest hit by the COVID-19 epidemic in Africa, has recorded about 1.7 million cases of COVID-19 and over 57,000 deaths. However, the country with a population of about 58.5 million people has only injected 183,000 doses of the vaccine to its people, as of June 9, according to the World Health Organization (WHO). South Africa is also one of the countries that is campaigning to give up patents for a COVID-19 vaccine to allow all countries to produce generic versions at low cost. “If we want to save lives and end the pandemic, we need to expand and diversify our production, put medical products into treatment, and fight and stop the pandemic for as many people as possible,” the president said. South Africa Cyril Ramaphosa speaks at a meeting with G7 countries in the UK on June 13.

Volunteers injecting experimental vaccine Covivac. Photo: General Writing Domestic vaccines can reach 20-30 million doses/year According to the Ministry of Health, so far, the country has two manufacturers researching and developing vaccines against Covid-19.
The Nanocovax vaccine of the Nanogen Pharmaceutical Biotechnology Joint Stock Company has been approved for a phase 3 clinical trial (TNLS). In the past few days, the Military Medical Academy has administered experimental injections to volunteers aged 18.
According to the research outline, phase 3 will test on about 13,000 volunteers in many provinces and cities such as Hanoi, Hung Yen, Long An, Tien Giang, etc. In the North, the Military Medical Academy will act as the focal point for deployment. at Military Medical Hospital 103 and Hung Yen province’s preventive health center deployed locally. The southern area will be professionally handled by the Pasteur Institute in Ho Chi Minh City, in collaboration with the preventive health centers of Long An and Tien Giang provinces.
At the Military Medical Academy, there are currently more than 6,000 volunteers registered to participate in the trial, of which more than 600 people have been screened and are eligible to participate. In the immediate future, in the first phase of the TNLS phase 3, the Military Medical Academy will test 1,000 people. According to the Military Medical Academy, before that, in stages 1 and 2 of the Nano Covax vaccine trial, 100% of people who injected immunity were protected against the attack of the SARS-CoV-2 virus.
In the phase 3 trial, the Nano Covax vaccine was administered to volunteers from 18 years of age, and there was no maximum age limit for the trial participants. Currently, the oldest person to register for TNLS injection phase 3 is 83 years old. Nano Covax vaccine will also be administered to volunteers with chronic diseases such as hypertension, diabetes (stable disease, do not inject during acute phase) to evaluate the results of immunogenicity. fluid, post-injection reaction… The results of the phase 3 clinical trial are the basis for the Ministry of Health to grant emergency permits and widely inject people to prevent the Covid-19 epidemic, which is expected in the fourth quarter of this year. Earlier, during a working visit to the Military Medical Academy, National Assembly Chairman Vuong Dinh Hue asked the Military Medical Academy to continue to closely coordinate with relevant ministries and sectors to urgently accelerate the implementation of clinical trials. Preparing phase 3 of Nanocovax vaccine, striving for early results to have a preventive vaccine for the community. However, when manufacturing, vaccines must ensure superiority in antibody generation time, with the shortest number of days; minimize side effects to a minimum, especially for people with weak health and underlying diseases; at the same time, must be able to resist and destroy future mutations. In addition, the COVIVAC vaccine of the Nha Trang Institute of Vaccines and Biologicals, is currently in the first phase of the TNLS and is about to be transferred to the second phase of research in Thai Binh.
According to the Ministry of Health, the COVIVAC vaccine is expected to produce about 6 million doses per year and can increase capacity when invested. Meanwhile, with the Nanocovax vaccine, which is expected to produce about 20-30 million doses per year, Nanogen Pharmaceutical Biotechnology Joint Stock Company can increase its capacity when invested.
A vaccine is coming soon that only requires one dose
Information from the Department of Science and Technology (Ministry of Health), a Vietnamese enterprise has discussed and negotiated with the US manufacturer on conditions for transferring technology to produce Covid-19 vaccine from mRNA essence. It is known that this vaccine only needs to be injected with a single dose of 5 mg, has high protection (based on the results of TNLS phase 1, 2), has a storage temperature of 20 – 80 degrees Celsius, currently the vaccine has been tested. end of trial phase 1, 2).
The first factory following the manufacturer’s technology standards will increase the capacity of 100-200 million doses/year, and is expected to start production from the end of 2021 or the first quarter of 2022. In addition, the No. 1 Vaccine and Biological Products Company Limited (VABIOTECH) is also negotiating with a Japanese partner to receive the transfer of vaccine production technology to Vietnam. In addition, VABIOTECH signed an agreement with the Direct Investment Fund of the Russian Federation on the closure of Sputnik-V Covid-19 vaccine tubes from semi-finished products with a scale of 5 million doses/month starting from July 2021. , towards transferring production technology with the scale of 100 million doses/year.
According to Minister of Health Nguyen Thanh Long, vaccines are an important weapon to bring life back to normal. Therefore, the Politburo has a policy on import, research, production and technology transfer for vaccines. Along with creating maximum conditions and quickly solving procedures for businesses and localities to import vaccines, Vietnam also promotes research and domestic production of vaccines. Vietnam is one of the first four countries in the world to isolate the SARS-CoV-2 virus, paving the way for research and production of vaccines, and many positive prospects for people to soon receive domestic vaccines. In addition, the Ministry of Health has worked with many foreign partners, negotiated to buy vaccine copyrights, transfer technology so that Vietnam can get the vaccine as soon as possible and be independent in the source of vaccines used in the country.
Recently, the Ministry of Health has negotiated with Johnson & Johnson Corporation with the hope that this unit will transfer technology to set up a vaccine factory in Vietnam. According to Minister Nguyen Thanh Long, many large corporations in Vietnam want to participate in the global vaccine supply chain. Vietnam is also one of more than 40 countries that can produce vaccines for the vaccination needs of the people, so the vaccine production experience of Vietnamese factories is guaranteed. Vietnam’s national vaccine management system (NRA) has also been certified as meeting standards by the World Health Organization (WHO). Johnson & Johnson’s side commits that after working with the Ministry of Health, it will make efforts to implement solutions to speed up the supply process through the COVAX mechanism, so that Vietnam can have Johnson & Johnson’s vaccine as soon as possible. However, Minister Nguyen Thanh Long also said that, to ensure vaccine security, one of the very important issues is to ensure a sustainable financial source for vaccines. Therefore, the Minister wishes that the community, authorities and businesses continue to support the Vaccine Fund. Vietnam has self-produced many vaccines and put them into the expanded vaccination program, contributing to the eradication and repelling of many dangerous diseases. This is the premise for the successful production of a Covid-19 vaccine. In fact, the research and production of vaccines against Covid-19 faces many difficulties and challenges, but this is the inevitable path we must go if we want to actively supply vaccines to serve the people. Over the past time, the Ministry of Health and State management agencies have created all conditions for administrative procedures for units to conduct vaccine production in the most favorable way. We can fully expect a “made in Vietnam” vaccine because at the moment, everything is going well.

Senior Advisor of the Center for Emergency Response to Public Health Events, Assoc. Tran Dac Phu The success of a vaccine depends not only on the manufacturer, researcher, and manager, but also on the social community. Therefore, we call for the cooperation of society, all people with the health sector to have a clinical trial research program, first of all, to be safe and effective to have a product soon. vaccines produced by Vietnam for the community.

Deputy Director of the Department of Science, Technology and Investment (Ministry of Health), Dr. Nguyen Ngo Quang

People wear masks to prevent COVID-19 infection at a market in Srinagar, India, June 14, 2021. Photo: THX/VNA The most severely affected country is still the US with 615,247 deaths out of a total of 34,335,515 infections. Next is India with 377,061 deaths out of 29,617,058 cases. Brazil ranks third with 488,404 deaths out of 17,454,861 patients. As a percentage of population, Peru has the highest mortality rate, with 573 deaths per 100,000 inhabitants. Next is Hungary with 310 people and Bosnia-Herzegovina with 289 people/100,000 people. By region, Latin America and the Caribbean are currently the epicenter of the world’s epidemic, with more than 1.2 million deaths in over 35.1 million infections. Next is Europe, with over 53.6 million people infected with COVID-19, including over 1.15 million deaths. North America has over 625,800 deaths in over 34.8 million infections. Asia recorded over 540,400 deaths in over 38.4 million infections. The Middle East has over 146,400 deaths, Africa has recorded over 134,900 deaths, while the number of deaths in Oceania is over 1,100. On June 15, Thailand recorded 3,000 new infections, including 2,995 domestic infections. On the same day, the country had another 19 deaths. Prime Minister Prayut Chan o-cha said the government has ordered 100 million doses of vaccine and aims to vaccinate 50 million people, or 70 percent of the population, this year and is buying more to expand immunization to 80 – 90% of the population next year. On the same day, the Lao Ministry of Health said that the country recorded 15 new cases of COVID-19 in the past 24 hours, bringing the total number of cases nationwide to 2,025. Of the 15 new cases, 6 were community infections in the capital Vientiane and 9 imported cases were immediately isolated. According to the Lao Ministry of Health, the failure of a part of the people to strictly comply with epidemic prevention regulations is the cause of new cases in the community. To date, more than 1 million Lao people have received at least one dose of the COVID-19 vaccine. A vaccination site against COVID-19 in Phnom Penh, Cambodia. Photo: AFP/VNA In the past 24 hours, Cambodia recorded an additional 495 cases of COVID-19 and 13 deaths from this disease. Although the epidemic situation in Cambodia is still complicated, the Phnom Penh capital government still decided to allow the resumption of all business and trading activities at the state-managed markets in the city. The Cambodian Ministry of Health said that in the next few days, the number of people vaccinated against COVID-19 will reach 3 million and the country is aiming for 10 million people to achieve herd immunity. According to the ministry’s report, so far 2,939,543 people in Cambodia have been vaccinated, or 29.4% of the total 10 million adults expected to be vaccinated against COVID-19. The number of new COVID-19 cases in Malaysia has been on a downward trend in recent days, after hitting record highs in May. Malaysian Health Ministry data released on June 15 confirmed an additional 5,419 cases. COVID-19 in the past 24 hours, bringing the total number of cases in the country to 667,876, including 3,968 deaths. The Malaysian government announced on June 15 that it had granted emergency use authorization for one-shot COVID-19 vaccines developed by CanSino Biologics (China) and Johnson & Johnson (USA). Malaysia is speeding up its vaccination program in tandem with strict lockdown measures to prevent the spread of COVID-19. As of June 14, this Southeast Asian country has administered at least one dose of COVID-19 vaccine to 3.28 million people, or 10% of the population. Vaccination against COVID-19 in Seoul, South Korea. Photo: AFP/VNA South Korea on June 15 recorded 374 new infections, bringing the total number of cases nationwide to 148,647. The country is planning to launch a trial of a new social distancing mechanism within three weeks, starting from the beginning of next month, while trying to prevent a spike in daily new infections. Accordingly, South Korea will lift the current ban on gatherings of 5 or more people and increase it to 8 people. Restaurants and cafes can stay open until midnight in the capital Seoul and surrounding areas, 2 hours later than the current curfew from 10pm. Currently, the capital Seoul and the surrounding area, along with the city of Daegu as well as the resort island of Jeju, are applying social distancing level 2 out of a 5-level scale, while the remaining areas are at level 2. 1.5. Mass gatherings of 5 or more people are prohibited. To date, about 13 million South Koreans, or 25% of the population, have received the first dose of the vaccine. Meanwhile, the Japanese Government has approved a new policy on increasing support for foreigners residing in Japan who have difficulties and obstacles in vaccination against COVID-19. Accordingly, the country will step up support and guide foreigners who are not familiar with the vaccination registration process at their places of residence, as well as have difficulties in contacting the vaccination department. In addition, the government will also promote the implementation of a multilingual portal on COVID-19 prevention measures. The Hong Kong government (China) has announced that it will relax the strict restrictive measures imposed since July last year for ships and boats docked at this Asian shipping hub. According to the Hong Kong maritime authority, from June 15, the crew of ships and boats that dock in this city for fuel or food will be exempt from restrictive measures depending on the situation. A COVID-19 test site in Hong Kong, China. Photo: AFP/VNA Israel has officially lifted the mandatory mask wearing in public places since June 15, after more than a year of implementation. Accordingly, buildings, offices, schools, hotels… will not require employees or visitors to wear masks when in this enclosed space. However, wearing a mask is still applied in a few special cases, for example, people who have not been vaccinated against COVID-19 who visit patient care facilities are at high risk of death if infected. infected, people on the way to quarantine or passengers on the plane. Earlier, on April 18, the Israeli Government also lifted the mandatory mask wearing rule outdoors and from June 1 lifted all social distancing measures after more than a year of application. Thanks to an effective vaccination campaign, the number of COVID-19 patients and the infection rate in Israel have dropped to a very low level. Also on June 15, the Indian Ministry of Health announced that it had recorded an additional 60,471 cases of COVID-19 in the past 24 hours, marking the eighth consecutive day that the number of new cases across India was below the threshold of 100,000 cases. Currently, the total number of COVID-19 cases in this South Asian country has reached 29,570,881 cases. Also in the past 24 hours, with an additional 2,726 deaths, the total number of deaths from COVID-19 in India has increased to 377,031 cases. In the capital New Delhi, after recording a sharp decrease in the number of new cases and deaths from COVID-19 in the last 2 weeks, restaurants and shops were allowed to reopen from June 14 with the evening hours. maximum 50% capacity. However, schools, educational facilities, swimming pools, gyms and public places remain closed. In Europe, the final stage of Britain’s COVID-19 lockdown lifting will be postponed to July 19 instead of June 21 as originally planned. The decision was taken as the UK recorded an increasing number of new cases of COVID-19 due to the emergence of the contagious Delta variant first detected in India. Scientists advising the British Government warn that the number of people needing hospital treatment due to COVID-19 will increase sharply again if the final phase of the blockade easing schedule takes place on June 21. according to the plan. According to the restrictions imposed to prevent COVID-19 in the UK, outdoor events are limited to a maximum of 30 people, indoor events up to 6 people. However, 15 pilot events are on track to ease the lockdown as planned, including upcoming EURO 2020 matches and art and music performances. Those attending these events must present a certificate of vaccination or test negative for the SARS-CoV-2 virus. Some regions in Russia have tightened restrictive measures to prevent the spread of the COVID-19 epidemic, while focusing on strengthening the response capacity of hospitals in the event of an increase in hospital admissions after the outbreak. as the number of new infections skyrocketed. On June 15, Russia added 14,185 new infections, of which 6,805 were in Moscow, bringing the total number of cases across the country to 5,236,593. In the past 24 hours, Russia also recorded an additional 379 deaths from COVID-19, bringing the total number of deaths to 127,780.

Vaccination against COVID-19 is given to a health worker in Khartoum, Sudan. (Photo: THX/VNA) According to the Vietnam News Agency correspondent in Africa, on June 14, President World Bank (WB) David Malpass had a meeting with the African Union (AU) COVID-19 Vaccine Procurement Task Force (AVATT) to discuss ways of cooperation to promote the vaccination against COVID-19 in Africa, of which WB will support the AU to deploy 400 million doses of vaccination Johnson & Johnson vaccine . Previously, on March 28, AVATT signed an agreement to buy 400 million doses of Johnson & Johnson’s one-shot vaccine with a financial guarantee of $2 billion from the African Export-Import Bank (Afreximbank). The World Bank and the AVATT Group agreed to speed up all administrative procedures to ensure African countries have access to vaccines as soon as possible. The agreement between the World Bank and the AVATT Group will support AU Member States to implement immunization, including domestic distribution (logistics and storage in accordance with cold chain requirements), ensuring systems, energy necessary capacity and capacity for vaccination, promoting propaganda campaigns so that people are ready to receive the COVID-19 vaccine. Dr. John N. Nkengasong – Director of the Africa Centers for Disease Control and Prevention (Africa CDC) and member of AVATT – said the number of Johnson & Johnson vaccines reached under the agreement is an important key to directing aim to immunize at least 60% of Africans. Achieving this goal is a prerequisite for saving the lives and livelihoods of the people of Africa, safely reopening the continent’s economy, and continuing the continent’s economic development agenda. With more than 41 countries at various stages of finalizing their vaccine orders, and with increasing vaccination momentum, it is essential that countries can organize full vaccinations for their populations quickly and with affordable prices. Mr. Strive Masiyiwa – AU special envoy and AVATT coordinator – said that the decision to cooperate with AVATT by the World Bank was made after the US announced the sharing of COVID-19 vaccine, which means that countries can rest in peace. more concerned about access to and financing of needed vaccines. Under the AVATT structure, AU member countries are allocated vaccines based on population size through a collective procurement mechanism. These doses complement vaccines offered through the COVAX Mechanism – which aims to provide vaccines to 30% of the population of the participating countries – allowing AU Member States to achieve their continental vaccination targets. AVATT was established on November 6, 2020, with the task of finding the necessary funding and ensuring equitable access to the COVID-19 vaccine for AU member countries.

The trend of “Covid-19 vaccine tourism” is flourishing in many places (Photo: FORBES) After more than a year of being “locked up” because of Covid-19, the world is witnessing the blooming of the “Covid-19 vaccine tour”. Is this type really the key to reviving tourism or is it bringing a lot of unpredictable potential? New trend Since December last year, Mr. Enno Lenze, a German businessman and museum director, has been looking for many sources to get an early Covid-19 vaccine but wants to go abroad. Finally, the opportunity came to him. A tour company in Norway called World Visitor provided a travel package to Moscow, Russia to get the Sputnik V vaccine. Brother Lenze and 50 other Germans took the opportunity and went to Russia to get the Sputnik V shot. the first one in early April. This month, he and the others will return to Russia for a second injection. Many people seek out the Sputnik V vaccine by traveling to Moscow (Image: AP) “I have visited many places. I’m interested in space travel and I want to see Soviet-era spaceships,” Lenze told National Geographic. World Visitor also offers a three-week “wellness” tour package where guests can relax at a spa in Turkey between Covid-19 shots. Albert Sigl, co-owner of World Visitor, said that he has sold Covid-19 vaccination tours to about 600 customers from Germany and Switzerland, two European countries that currently have flights to Russia. According to Mr. Sigl, the company will continue to open Covid-19 vaccine tours to other countries when they open. In Austria, tour operator Impfreisen.at is also offering unconditional reservations for a series of holiday packages with “guaranteed rights to a Covid-19 vaccine”. For those who can’t afford it, Impfreisen even offers free rides to 1 in 10 people who book the cheapest package, if they can prove it’s financially viable. Last week, The Wall Street Journal of the United States reported that it did not take until New York City announced a plan to provide Covid-19 vaccination services to foreign tourists, the tourism industry from Texas to Florida already Heats up as tens of thousands of tourists from Mexico and many other countries come to these states to receive the Covid-19 vaccine. Some states in the US, including Texas, do not require vaccination applicants to present proof of residency status. According to the AP news agency, wealthy tourists, including politicians, TV stars, leaders of companies and famous players in Latin America, have come to the US to get vaccinated against Covid-19. People stand in line to check in at Silvio Pettirosso Airport (Paraguay) to Miami. Many Latin Americans who come to the US for vaccinations have friends or relatives who live in the US and can help them get vaccinated against Covid-19. (Photo: AP) Most Covid-19 vaccination tours are from Mexico to Texas. Mexican airlines have opened more routes to South Texas and increased frequency of flights. Flights to Houston, Dallas and San Antonio have also been booked weeks in advance and fares are also increasing significantly. In addition, the charter flight service to the US for vaccination is also flourishing in Mexico. Cindy Mijares, a 31-year-old jewelry designer from Monterrey, Mexico, said that like many of her friends, she booked a Covid-19 vaccination at a pharmacy in Texas. The Wall Street Journal, citing preliminary data from Mexico City International Airport, showed that in April, about 207,000 passengers departed for the United States, compared with 177,000 in March and 95,000 in February. in April were Houston and Dallas, with 41,000 and 26,000 passengers, followed by Los Angeles, Miami and San Antonio. People get a shot of Johnson & Johnson’s Covid-19 vaccine at a mobile vaccination center in South Beach, Florida (Image: TheBangkokPost) The wave of Covid-19 vaccine tourism also spread to Asia. Recently, many Thai tour companies have offered Covid-19 vaccination tours to the US and Russia. A Bangkok-based tour operator, Unithai Trip, offers packages ranging from 75,000 baht to 200,000 baht ($2,400 to $6,400) for tours to San Francisco, Los Angeles and New York, at extra prices. depending on the time interval between injections of each Covid-19 vaccine. Unithai Trip CEO Rachphol Yamsaeng told Reuters: “Johnson & Johnson only needs one shot, but 90% of travelers require Pfizer’s Covid-19 vaccine,” so it takes about 20 days between the first dose. first and second dose. Meanwhile, another tour operator, My Journey Travel, is offering a 10-day trip to San Francisco for Johnson & Johnson’s Covid-19 vaccine. This company information, in just three days of opening the tour, they received hundreds of calls to ask about this tour. The US is not the only destination to get a Covid-19 vaccine for Thais. Udachi, a travel agency, has offered a 23-day tour called “Vaccine Vacation in Russia” to get the Sputnik V vaccine for up to 210,000 baht ($6,700). Travel leverage? After more than a year of “freezing” because of Covid-19, some countries with tourism as the mainstay of the economy are looking to increase tourist numbers by offering travel packages with Covid-19 vaccinations. “Paradise” Maldives has pursued a “3-V” strategy to encourage tourists to “visit, vaccinate and relax” (Vist, Vaccine and Vacation). Maldivian tourism minister Abdulla Mausoom told CNBC this would provide visitors with “more convenience” when on vacation. Mr. Mausoom said that while only about 13% of Maldivians are fully vaccinated, about 90% of frontline tourism workers are vaccinated. This figure points to the importance of the tourism sector in the economic recovery prospects of the Indian Ocean “resort paradise”. According to I. Glenn Cohen, a professor at Harvard Law School and director of the Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics, traveling for medical treatment is not a trend. new save. The thriving medical tourism market has been around for many years. In the case of the Covid-19 vaccine, as long as the risk groups are protected first, vaccine-abundant countries can use them to restart tourism, but provided this is done carefully. kidney. “What matters is where the net benefits go,” he said. This benefit should benefit the poorest people in the community, not just the rich.” Although two doses of the Covid-19 vaccine may make countries retain tourists longer because it takes time for the body to produce an immune response, the following travel activities should not be rushed. vaccination. Passengers disembark from a plane at Velana International Airport in Male, Maldives, July 15, 2020. Maldives is currently encouraging foreign tourists to return with a “3-V” strategy that combines visits, vaccinations and resorts. (Photo: GETTY IMAGE) Professor Cohen said he was a bit concerned and advised tourists who had just been vaccinated against going to markets or shopping malls right away. On May 6, New York began promoting itself as a tourist destination for those seeking a Covid-19 vaccine. Previously, from April, the Florida state government announced that it was canceling the requirement to be a resident of the state to receive the vaccine after the first wave of vaccination tourism. In Alaska, in an effort to boost local tourism, Governor Mike Dunleavy said visitors can get a free Covid-19 vaccine at the state’s main airports starting June 1. Mexican travel companies, already reeling from the pandemic, quickly recognized the opportunity. Eduardo Paniagua, head of the Mexican tourism industry association, said that in March and April, travel agencies sold tours to the US to 170,000 people, most of whom traveled for injections. Covid-19 vaccine. The US-Mexico border remains closed to non-essential land travel, but travelers can still travel by air. More than just coming to get vaccinated, travel to the US has a direct impact on local economies. Vaccinated tourists spend money on airline tickets, hotel stays and spend more time shopping and eating. These special tours are helping revive the economies of places like Texas’s Rio Grande Valley, which have been hit hard by a year of border closures. Saul Sanchez, co-owner of Carats in McAllen, Texas, helps a customer try on jewelry. The business of the stores declined when the border closed and was buoyed by the return of Mexican tourists (Image: WSJ) Before the pandemic, Mexican tourists to McAllen, Texas typically contributed about $1 billion of the country’s $3.5 billion average annual retail sales, said Steve Ahlenius, president of the local chamber of commerce. city. Although locals have the lowest income in the US, the area is a top destination for wealthy Mexican tourists. Is it legal? At a glance, it can be seen that Covid-19 vaccination tourism is an attractive form to restore the tourism industry. But many people are also questioning the legitimacy of this type of tourism, the risks to tourists when participating in vaccination tourism and even its ethics. At this time, no formal arrangements have been made to ensure that foreign tourists are vaccinated against Covid-19 in the country they travel to. So tourists getting vaccinated could be frustrated and risk losing money. Reuters quoted Thailand’s Tourism Ministry on May 5 warning, travelers need to carefully check vaccination travel packages because the entry regulations in each state in the US are different. Euronews reported last month that Kremlin spokesman Dmitry Peskov said the government would consider a vaccination tourism program, but that Russian citizens were an “absolute priority”. Meanwhile, information on social media about vaccination tours for tourists from Turkey to Serbia has been denied by the Turkish Ambassador to Belgrade and the Serbian Embassy in Ankara. They confirmed that only Turks with a residence permit in Serbia are allowed to receive the Covid-19 vaccine. Some countries have clearly announced that they do not welcome tourists to receive Covid-19 vaccines. In the UK, for example, the Covid-19 vaccine can only be administered through the public health system and must wait until a doctor’s appointment is received. At the appointment, the vaccinated person needs to confirm personal information, such as home address. It is possible that many other countries have adopted similar measures. In some respects, Covid-19 vaccine tourism can contribute towards the common goal of ending the Covid-19 pandemic soon. So far, the WHO has urged Covid-19 vaccine manufacturers to keep their commitments to equitable distribution of vaccines. But with some richer countries starting to monopolize the stockpiling of excess vaccines to make a profit, Covid-19 vaccine tourism will only prolong the wait for access to Covid-19 vaccines in many parts of the world. , especially in poor countries, and exacerbated the imbalance of supply and demand for Covid-19 vaccines. These consequences will likely slow down efforts to end the Covid-19 pandemic, which WHO insists can only be achieved by global cooperation in vaccine sharing.

(Source: Getty Images) National Advisory Committee on Immunity of Canada (NACI) on June 1 announced updated guidelines allowing the combination of preventive vaccines COVID-19 licensed in the country in most cases. Under the new guidelines, people who have received their first dose of the AstraZeneca vaccine can receive a second dose of the Pfizer-BioNTech or Moderna vaccine, unless they are pregnant. So far, Canada has allowed the use of 4 types vaccine against COVID-19 of pharmaceutical companies Pfizer, Moderna, AstraZeneca and Johnson & Johnson. The new guidelines also say that the Pfizer and Moderna vaccines can be used in combination for both the first and second shots. However, the NACI does not recommend a second dose of the AstraZeneca vaccine following the first dose of the Pfizer or Moderna vaccine for safety reasons and limited data on the use of this combination. Speaking at a press conference on June 1, Canada’s public health official Theresa Tam said, “NACI is working to quickly adopt new guidelines for vaccine use in the country to ensure optimal protection of people in the context of the changing epidemic situation.” Tam also added that although according to the new NACI recommendation that vaccines can be safely used in combination, people should use the same vaccine for two injections if possible, especially Pfizer’s vaccine. or Moderna. According to Ms. Tam, the use of vaccine combinations is not a new concept and has long been applied by public health to many vaccines. The updated NACI guidelines are based on current studies from Spain and the UK that show the combination of AstraZeneca and Pfizer vaccines to be safe and effective against COVID-19. As of the afternoon of June 1, 2021, 21,942,111 Canadians, equivalent to 57.75% of the country’s population, received the first dose of the COVID-19 vaccine and 2,144,126 people, equivalent to 5.64%, second injection. The disease situation in the North American country is also continuing to decline with the number of new cases per day in the last 7 days being below 2,700 cases, the average death per day decreased to 39 cases. As of the afternoon of June 1, Canada recorded 1,248 new cases, bringing the total number of COVID-19 cases in the country to 1,382,822, of which 25,565 people have died. On the same day, according to the Vietnam News Agency correspondent in Buenos Aires, an adviser to Argentine President Alberto Fernandez, Cecilia Nicolini, said that she is considering the possibility of cooperating with Cuba to produce a vaccine against COVID-19 researched and manufactured by Cuba in order to prevent COVID-19 infection. distributed to the Latin American market. In an interview with Sputnik news agency, Ms. Nicolini announced that during the recent visit to Cuba by the Minister of Health Carla Vizzotti, the Argentine side was introduced to the progress in the process of research and development of vaccines. COVID-19 of Cuba, and affirmed Argentina’s desire to cooperate in the production of this drug so that it can meet the actual demand as soon as possible, not only in Cuba and Argentina but also in other countries in the world. area. Currently, Cuba has 5 candidates for COVID-19 vaccine, namely Soberana 01, Soberana 02, Soberana Plus, Mambisa and Abdala with very positive prospects, in which candidates Soberana 02 and Abdala have successfully finished the phase. clinical trials 1 and 2 with high rates of safety and efficacy. According to Nicolini, in the coming days, the Cuban side will present data analysis of the third phase of testing of these two vaccines and the two sides will conduct negotiations on the possibility of mass production. Currently La Soberana 02 and Abdala are the only two COVID-19 vaccines researched by a Latin American country that have entered the final phase of clinical trials.

The tour is organized in the form of Free & Easy, including airline tickets to the US and hotel rooms of 3 stars or more standard; Covid-19 test fee before entering the US; visa fees to the US; Travel insurance and guides support registration, procedures for vaccination against Covid-19 vaccine in the US. The price offered is 44.99 million VND/pax for the 8 day 7 night tour. This is the first travel agency in Vietnam to organize a tour to the US to get vaccinated against Covid-19. Other companies are also listening to the situation to organize similar tours. Some travel companies in Vietnam are also considering and learning about US tours to vaccinate Previously, in the region, some Thai travel companies also offered vaccination tours in the US. Specifically, the company My Journey Travel offers a package “Covid-19 vaccine tour”, a 10-day flight to California (USA). With a cost of 2,400 USD/person (about 55 million VND, excluding airfare), so far, more than 200 people have booked. Prices above include a single dose of Johnson & Johnson’s vaccine. Another company, Unithai Trip in Bangkok (Thailand), also launched tour packages from 75,000 baht to 200,000 baht ($2,400 to $6,400, equivalent to 55 to 147 million dong) for flights to San Francisco, Los Angeles. and New York. According to the VNA, tourists from other countries are flocking to the US to combine tourism with vaccination. To date, tens of thousands of tourists from Mexico and some other countries have flown to Texas and Florida to get vaccinated. Or, thousands of wealthy tourists, including politicians, TV stars, leaders of companies and corporations in Latin America, have come to America to get vaccinated. Some chartered private planes to go to the US. Therefore, organizing tours combined with vaccination is a business opportunity for tour operators. Vaccination demand soars Regarding this issue, Mr. Nguyen Trung Khanh, General Director of Vietnam National Administration of Tourism, in PLO newspaper, said that it is normal to go abroad with Vietnamese tourists, not banned. As for entry, they must comply with regulations in the context of the complicated development of the Covid-19 epidemic. According to some companies and travel experts, the above price of 44.99 million VND is only suitable for those with conditions, because that price does not include food, travel, and personal expenses at the hotel. America. Not to mention, depending on the vaccine, you have to wait for the second shot. With the Johnson & Johnson vaccine, only one dose is needed, but if you want to get the Pfizer vaccine, you have to wait 20 days to get the second shot. After completing the injection, when returning to Vietnam, the tourist is still quarantined for 21 days at an isolation facility and then monitored for 7 days at home according to current entry regulations of the Health sector and the authorities. Thus, a complete trip with vaccinations in the US to be able to contact the community takes from 1 and a half to nearly 2 months, not to mention the cost of isolation when returning home. Bao An

Anthony and his wife invited 9 people to a luxurious gala dinner at their apartment. Snacks such as fruit jelly are contained in large syringes, while drinks are poured into boxes labeled Pfizer, Moderna or Johnson & Johnson – 3 companies that provide Covid-19 vaccines, according to NY Post. “We waited too long to meet everyone. It’s time to have fun again,” Anthony said. The party was planned by celebrity event organizer Amanda Orso. Orso said she has coordinated similar events in other cities like Miami, Florida. “It’s not too ostentatious or cheesy, but elevated to a more elaborate party,” Orso said. Laurence Anthony’s party was nicely decorated. Photo: NY Post. Like Laurence Anthony, Karina Freedman (51 years old, from Manhasset, Long Island), owner of two skin care clinics, also plans a “vaccination party” for mid-May 2021. “Everyone can finally get together and celebrate. Surely everyone will be very happy,” Freedman shared. Freedman plans to give attendees gift bags containing healing crystals with the wishes “Be happy, stay healthy, good luck”. While many people hire event planning services to assist with planning, others only do small parties with relatives and friends. Leticia Rossi and Guilherme Baglioli (living in Austin, Texas) moved into a new home in January 2020. Due to the pandemic, the young couple could not hold a housewarming party. When their areas reopened from March 10 according to Governor Greg Abbott’s decision, Rossi and Baglioli joined a group of close friends for a dinner at home. All had previously been vaccinated. “We finally got to hug and talk to each other. It’s good that everyone is at peace,” Rossi wrote on his personal Instagram page. However, experts say that gathering and partying at this time is too early and risks a stronger outbreak. Although vaccination has been widely conducted and the number of new cases has decreased, the Covid-19 epidemic is still raging in many places across the United States, according to The Guardian. In early March 2021, despite criticism from the US Centers for Disease Control and Prevention (CDC), Alabama, Texas and Mississippi still decided to lift epidemic prevention restrictions, according to the CDC. BBC. Florida beaches are packed with people. Photo: Reuters. In Florida, many young people flock here to party and celebrate spring break when the state lifts anti-epidemic measures. Quite a few people said they were “not in the at-risk group”. Therefore, they are not concerned about Covid-19. And in Las Vegas, after a long closure, pool parties are “covering” again as more and more people are vaccinated. “Four months ago, Las Vegas was like a ghost city. Now pool party participants have to distance themselves. We are required to wear masks outside the pool area,” Alyssa Waggoner (25 years old) told Insiders.

Not only does not lose the inherent masculine appearance of men, the Gucci Jackie 1961 bag in black leather makes the male singer Harry Styles more prominent, attracting attention from the first seconds. The late-night talk show with extremely attractive topics has long become an indispensable spiritual dish of every home. For the first time, Gucci joins top stars such as Brand Ambassador Harry Styles, actress Awkwafina, actress-filmmaker Dakota Johnson, actress Diane Keaton, athlete-businesswoman Serena Williams and Actress Sienna Miller gathered at the talk show to discuss their latest achievements, and of course, share interesting stories around their favorite handbag model to the audience. Gucci Beloved is Gucci’s newly launched campaign with the focus on main Gucci handbags such as GG Marmont, Dionysus, Jackie 1961, Gucci 1955 Horsebit. The Awkwafinia actress showed off her luxurious aura with the elegant white GG Marmont bag. Actress Dakota Johnson elegant with Gucci’s Dionysus bag. “ We decided to bring the concept of “beloved” in a more humorous way in this campaign, inspired by the handbags that are the main characters in my life and those of the people I love. love them “, designer Alessandro Michele confided. “ Back to the talk show, where the bags play the main characters, the real stars. They are often named after influential women. For now, we will bring them to the show and put them on par with the guests like the two stars in attendance “. Actress Diane Keaton put on a strong menswear-style suit model with a Gucci 1955 Horsebit bag. Actress Sienna Miller beamed with a Gucci Jackie 1961 bag with GG Supreme motifs. Meanwhile, female tennis player – businessman Serena Williams is gentle in a floral pattern dress and a black leather GG Marmont bag. The handbags that appear in the Gucci Beloved campaign, are carefully cared for by Creative Director Alessandro Michele to harmonize the modernity of the product while preserving the heritage value of the fashion house. Therefore, they are timeless, never-out-of-fashion fashion accessories that any girl aspires to own. “ I really love and adore my bags “, said designer Alessandro Michele. “ Perhaps, for me, they have always been my greatest love, my favorite accessory. That’s why I call some of my bags ‘Beloved’. This name comes from my actual experience and my love for them “. Notable designs in the Gucci Beloved campaign include the Dionysus bag with the details of two tiger heads in the shape of a horseshoe, likened to a triumph in honor of the Greek god Dionysus who crossed the Tigris river on the back of a tiger sent by Zeus. Next is the Horsebit 1955 bag model that impresses with the famous horsebit motif of the Gucci fashion house. Meanwhile, the GG Marmont bag is easily identifiable with the GG buckle. Finally, the famous 1961 Jackie bag with its crescent moon design will be considered a timeless item but still accentuated with extremely modern lines. Posts: To Hoang Bao

People are vaccinated against COVID-19 by Johnson & Johnson Company in Chicago, Illinois, USA on April 6, 2021. Photo: AFP/VNA New York City Mayor Bill de Blasio recently announced the city will offer COVID-19 vaccination services to foreign visitors at mobile vaccination centers, starting this summer. But before that time, tourists, mostly Mexicans, have flocked to the US for the opportunity to get vaccinated. Up to now, tens of thousands of tourists from Mexico and some other countries have “landed” in many states such as Texas and Florida to be vaccinated. Some states in the US, including Texas, do not require visitors to present proof of residency. USA Today previously reported that thousands of wealthy tourists, including politicians, TV stars, leaders of companies and corporations in Latin America, have traveled to the US to receive vaccines. Some rent a private jet to go to the US. Mexico has so far only vaccinated enough doses for about 6% of the population and the vaccination program is only applicable to people over 60 years old. Many tour operators in Mexico have promoted travel packages including vaccinations to the US. “Enjoy Dallas and get a COVID-19 vaccine,” a travel agency ran an ad. Mexican airlines also recently increased flights to south Texas to serve the growing demand of travelers. A Thai travel company is also offering a package “COVID-19 vaccine tour” to the US. More than 200 people are already booked, at a cost of $2,400 per person for a 10-day trip to California that includes a single dose of Johnson & Johnson’s vaccine. The above amount does not include the cost of airfare.

Unithai Trip Company in Bangkok offers travel programs from 75,000 baht to 200,000 baht ($2,400 to $6,400) for trips to San Francisco, Los Angeles and New York (USA), with prices depending on the range. waiting time between injections. The beaches in Phuket, Thailand are empty of tourists. Source: Reuters A group of guests will depart next week, said Rachphol Yamsaeng, owner of Unithai Trip. Most of the people who inquired about this tour asked for the Pfizer vaccine, so about 20 days between the first and second dose. “Travel companies are having a hard time. We have to do whatever we can,” said Rachphol Yamsaeng. In addition to Unithai Trip, My Journey Travel is offering a 10-day trip to San Francisco for a Johnson & Johnson vaccine, which the company says it received hundreds of calls in three days. Another company, Udachi, has offered a 23-day “VACCation in Russia” program to vaccinate Sputnik V for up to 210,000 baht ($6,700). However, the Tourism Ministry of Thailand has warned that customers should carefully check vaccination packages, as US regulations can vary from state to state.

Many Mexican airlines also increase the frequency of flights to the United States to serve the needs of tourists to get vaccinated early. In Thailand, “vaccination tours” are also being offered by many tour operators. A travel agent said it had just arranged a tour for 200 guests to California to get a Covid-19 vaccine. On average, each visitor has to pay $2,400 for a 10-day trip, including a dose of Johnson & Johnson vaccine, without airfare. These vaccine tours are said to be helping to revive the economy in some parts of Texas, as more tourists book hotels, shop locally and visit attractions while there. while waiting for vaccination. Many foreigners flock to the US to get a Covid-19 vaccine. Photo: Getty. Earlier, New York Mayor Bill de Blasio said the city would soon offer Covid-19 vaccination services to tourists this summer when the city reopens. However, many people still want to inject earlier for peace of mind. According to information on the website of the US State Department, medical tourism is considered a valid reason to visit the country. States like Texas and Florida are popular destinations because they don’t require residency certificates to get the Covid-19 vaccine. Two of the many people who came to the US to get the vaccine successfully were Virginia Gónzalez and her husband. The two flew from Mexico to Texas, then took a bus to the vaccination site. In total, to receive 2 injections soon, the couple traveled more than 2,200 km. “This is a matter of survival. Mexican officials don’t buy enough vaccines, it’s like they don’t care about their own people,” Gónzalez said. Mexico has now vaccinated 6% of its population, with priority given to those over 60. In addition to the US, Russia is also a country chosen by many people who want to be vaccinated soon. A 23-day tour from Thailand to Russia to get the Sputnik V vaccine costs about 210,000 baht ($6,700).

Sweating in the Sunday afternoon sun, visitors check in to the online system – no proof of residency is required – and right after that they get a free dose of Johnson & Johnson’s vaccine and receive get a vaccination card. Many tourists in need of vaccination have flown from abroad to Miami Beach, USA People are coming from all over Latin America like Ecuador, El Salvador, Venezuela, where the implementation of vaccination is slow or there is a shortage of vaccine supply. “In my country, Covid-19 is getting out of hand and there is not much chance that we will have access to a vaccine anytime soon,” Maria Bonilla, from the Republic of Honduras, told AFP on Saturday. . The 40-year-old accountant flew to Miami with her 63-year-old and 73-year-old parents. The three of them stood in line together, wearing masks. “We decided to look for a solution outside of the country,” Bonilla said. On Friday, 50-year-old Blanca Diaz, from Mexico, reached the same conclusion: “They’re just starting to vaccinate the elderly,” she said of the Covid-19 vaccination situation in her homeland. myself. Bonilla is acutely aware of her privilege to be able to travel with her parents for vaccinations. “Unfortunately vaccination has created a divide as some of us have access to health protection and others do not,” Bonilla said. Miami City Commissioner David Richardson, a Democrat, told AFP he had mixed feelings about tourists coming to Miami Beach to get vaccinated. He said: “I think we, the US government should help as many people as possible. My only concern is that it seems that people who can afford to buy plane tickets can come to the US and get vaccinated. right now but what about the poor people in South America?”. Richardson also requested, urging the US government to send the vaccine support abroad “so that everyone can access the vaccine, not just the people who can afford to come here”. On Sunday, the Johnson & Johnson vaccination counter had injected about 175 people. This is a popular vaccine brand among travelers because only a single dose is required. (According to TNN/Dan Tri)

Bran Castle – a popular tourist attraction in Transylvania, Romania – which is considered the inspiration for the famous Dracula novel series, has set up a Covid-19 vaccination center. According to a notice from the management, visitors can come for free injections every weekend in May without an appointment. Photo: Getty. In addition, tourists coming here will also be able to visit the castle’s gallery of 52 medieval torture instruments at no extra cost. However, vaccination is only available to Romanian citizens. Marketing director Alexandru Priscu said the campaign was meant to “make vaccinations more fun”. Photo: BBC. In the US, people can register for the Covid-19 vaccine when attending sports matches. On May 10, each audience present at the hockey game between the Philadelphia Flyers and the New Jersey Devil team had the opportunity to get a shot of the Johnson & Johnson vaccine. The campaign is also held at games by the Seattle Mariners baseball team or the Seattle Sounders football team. Photo: AP. On May 11, in the opening match at the home of St. Paul Saints in Minnesota, this baseball fan was vaccinated and given 4 vouchers to watch another game. Manager Derek Sharrer said: “This is a great opportunity for the audience to be vaccinated in a favorable way.” Photo: AP. In addition to fixed health stations, British people can register for vaccinations at churches. Twice a week, about 800 citizens can go to Poet’s Corner at Westminster Abbey (London, England) to receive medical staff’s help with Covid-19 vaccination. On its website, the monastery said that this vaccine site will accept individuals who make an appointment through the National Health Service, which is expected to operate until at least the end of June this year. Photo: AP. Salisbury Church in England is also part of the country’s vaccination campaign. After vaccination here, people have to stay for 15 minutes for medical staff to monitor the response. According to data from Our World in Data, more than half of the UK population has received at least one dose of the vaccine. Photo: Sky News. Since May, David Richardson, City Commissioner of Miami (USA), has launched an initiative to establish non-permanent vaccination points in the South Beach area. “We want to reach beachgoers and encourage them to change their mind about vaccination,” said Richardson. By the second day of the campaign, the registration points had consumed 125 doses of Johnson & Johnson vaccine and also used up 50 additional doses. Photo: Getty. Mr. Richardson said the campaign was heavily promoted on media and social networks. In addition to the target group of tourists coming to the Miami beach to relax, the city government also wants to mobilize neighboring people to come here to get vaccinated. “Some people come here in bathing suits, there are also people who come here to get vaccinated.” Photo: Miami Herald. The new vaccination site that is receiving attention from New York City public opinion is the bottom of a more than 28,000-meter whale model at the American Museum of Natural History. Those who register for vaccination here are given a voucher to visit the museum for free the next day. “This is the newest, hottest vaccination site right now,” New York City Councilmember Mark Levine wrote on Twitter. Photo: New York Times. On May 9, 200 doses of Johnson & Johnson vaccine were delivered to storage at the Arapahoe Basin ski area in Summit County (Colorado, USA). Visitors and Colorado residents will not need to register in advance to make a reservation. “Hopefully this will help the community continue the process of vaccination to overcome the pandemic,” said Tony Cammarata, head of the Arapahoe Basin patrol. Photo: Arapahoe Basin.

Before the debut, the female lead 50 shades attended a digital show of Gucci Aria in its spring outfit. She is a famous guest at the event. Johnson appeared on the virtual red carpet with Florence Welch, Lil Nas X and Anderson Paak. She wore a piercing Overture jumpsuit, showing off her physical advantage. The actress paired with an embroidered GG tulle underwear set costs $ 1,100. To complete the look, she combined a sparkling pink short-sleeved sequin jacket. Dakota Johnson wears a jumpsuit that goes through the Gucci event. Photo: @gucci, The Zoe Report. Grazia said that this outfit is the product of designer Kate Young. Less than 24 hours later, the American star wore another Italian fashion house outfit on the show The Beloved Show . This is a late-night chat show featuring a lineup of celebrities and a signature luxury brand bag series. “Johnson appeared as if she came out of the ’70s wearing a dark purple, pink, green sequin jumpsuit and a short-sleeved corset”, Grazia comment. She holds the famous Dionysus bag with the company’s signature GG motif. Johnson’s medium-sized mid-size bag sells for $ 2,590. Before that, the actress attended many Gucci shows. In addition, she also appeared at events, premieres in the design of an Italian fashion house. Dakota Johson has repeatedly shown the design of Gucci. Photo: People, ELLE. How to restore Gucci shoes worth 680 USD Restoring expensive shoes takes many steps. In particular, the cleaning of the inside and the outer shell are important.

The Rock is still the richest actor in the world. Last year, his income was $ 87.5 million, according to Forbes. Muscle star Dwayne Johnson, who for two years in a row holds the top spot on the list of the richest actors in the world has just spent $ 27.8 million (about 667 billion) to buy a monumental residence in Beverly Park. The newly purchased villa built in Mediterranean style, covers an area of ​​more than 1,600 m2 with 6 bedrooms, 11 bathrooms, both indoor and outdoor swimming pools, tennis courts, world-class gym, movie theater, music studio, lawn and lush gardens. Recently, the 49-year-old actor continued to be concerned with the intention of running for US President next term. A lot of Americans want a movie star Fast and Furious Contest and The Rock has mentioned this in many interviews in the past. The Rock intends to run for US President from 2017. The move to a new home is part of the actor’s plan to reach the upper class of the population. Beverly Park is home to many cult stars such as Denzel Washington, Sly Stallone, Rod Stewart, Eddie Murphy, Sofía Vergara. The newly bought mansion of The Rock was previously for sale for $ 30 million, but then the actor negotiated to reduce it to $ 27.8 million. This is really the dream residence of many people. Before that this mansion used to belong to rocker Alex Van Halen, who shaped this place since 1993. The living space of the villa is extremely quiet, avoiding any outside, it is like a resort. perfect maintenance.

EMA thinks vaccine is safe

The EMA had previously confirmed that the vaccine could indeed cause blood clots in very rare cases. But the possibility of blood clots with a very low number of platelets is only registered as a rare side effect. According to the experts, most of the cases involved women under 60 years of age. Therefore, the authority reiterated that the benefits of the vaccine to prevent Covid-19 should be rated higher than the risks of side effects. It was the second time that the EMA re-examined a corona vaccine after approval. Cerebral vein thrombosis had also occurred with the active ingredient in AstraZeneca. Here, too, the EMA stuck to its assessment that the vaccine was safe.

36.7 million vaccine doses for Germany

In the EU, delivery of the Johnson & Johnson vaccine only started last week. Numerous EU countries followed the manufacturer’s recommendation to wait for the EMA experts’ report before using it. The EU Commission has already ordered vaccination doses for 200 million people. Of these, 36.7 million vaccination doses are to be delivered to Germany and thus accelerate the vaccinations. Nationwide, according to registration data, 20.2 percent of the population have now been vaccinated at least once, according to the Robert Koch Institute (RKI). According to this, around 16.8 million people were vaccinated once, and around 5.6 million more received full protection with a second dose. Ten of the 16 federal states have already reached the 20 percent mark for first vaccinations.

Covid-19 vaccination for medical staff – Photo: Minh Anh The World Health Organization (WHO) has requested vigilance, monitoring, early detection and timely management of rare human events after Covid-19 vaccination with suspected immune thrombocytopenia. , scattered blood clots in the lumen, cerebral venous thrombosis. The rate of thrombosis after AstraZeneca vaccination is 4.6 / 1 million doses of the first injection, Pfizer-BioNTech Covid-19 vaccine is 0.2 / 1 million doses of the first injection. Thrombosis after AstraZeneca vaccination is mainly seen in women, in Germany there are 29 out of 31 women with thrombosis are women. The rate of blood clotting after AstraZeneca vaccination in young people is higher than in the elderly, especially in the age group 20-29. After vaccination AstraZeneca, the phenomenon of blood clotting seems less likely to occur in people over 60 years old, only about 0.2 / 1 million doses of the first injection. Complications of coagulation after AstraZeneca vaccination depend on genetic factors, underlying disease, lifestyle, medications, factor V Leiden (risk of blood clots). According to the clinical symptom guidelines, the above events are rare and usually appear 4 to 28 days after Covid-19 vaccination with persistent, severe headache; localized neurological symptoms; convulsions, blurred vision, or double vision; difficulty breathing or chest pain; stomachache; pain, swelling of the lower extremities. In particular, patients rarely present with bleeding, skin hemorrhage, or internal bleeding. The Ministry of Health believes that lower level medical facilities can completely handle the clotting phenomenon According to the Ministry of Health, at commune, ward, district or equivalent health centers of grade IV, people should be monitored after vaccination. If at least 1 of the above clinical symptoms appears, it is necessary to transfer the person after Covid-19 vaccination to a higher level or seek emergency treatment if any. In the case of the district hospital, district or equivalent grade III, after injection appears one of the above symptoms need to carry out the following tests: Count the platelet count; basic coagulation tests; quantitative D-dinmer assay; Ultrasound, X-ray exploration … In case of after injection, symptoms need to be transferred to higher level for treatment. At the provincial, city or equivalent level II health facilities, basic tests are needed to count platelet count, and basic coagulation test; quantitative D-dimer assay; imaging tests to assess thrombosis and bleeding; perform other exploration if available. In cases beyond the capacity of diagnosis and treatment, it is necessary to consult a higher level specialist. At the central grassroots level or equivalent grade I, the special class will take in people after vaccination with severe complications transferred by the levels, and carry out all necessary investigations for diagnosis and treatment according to the diagnosis and treatment guidelines of the Ministry of Health; Consult experts as needed. According to the Ministry of Health, by the morning of April 23, an additional 20,203 people were vaccinated against Covid-19 of AstraZeneca. Thus, from March 8 to now, a total of 128,610 people have been vaccinated against Covid-19 of AstraZeneca phase 1 and phase 2 in 28 provinces and cities and have not recorded any cases of blood clots later. injection.

Patient COVID-19 is being treated at a hospital in Bry-Sur-Marne, France, on April 15, 2021. Photo: AFP / VNA Prime Minister Castex confirmed there is evidence that contagion in the past 10 days has tended to decrease. Castex also announced that measures to restrict people from leaving the area within a 10-kilometer radius around the house will be removed from May 3. France is implementing a third blockade to prevent the spread of the SARS-CoV-2 virus, but this prevention measure is considered to be more relaxed than the previous two times. During the 3rd blockade, outdoor activities are still encouraged to improve the mental health of residents. Most of the non-essential stores, cafes, restaurants, and cultural venues are closed. In a new statement, Mr. Castex said that shops, certain cultural and sporting activities and cafes could be reopened from mid-May, depending on the disease situation in Vietnam. at that moment. The French Prime Minister also emphasized that the government will allow regional openings, starting with regions with low COVID-19 prevalence. National curfew from 7:00 p.m. daily remains in place until further notice. Mr. Castex noted this measure will be reevaluated in mid-May but the government has not put in place a firm schedule for easing. To date, France has recorded a total of more than 5.4 million cases of COVID-19, of which 102,164 died. Over the past few days, the number of COVID-19 cases requiring special treatment has been contained below 6,000. After a slow start, the COVID-19 vaccination campaign in France is accelerating, with more than 13 million people getting at least the first shot. From April 24, French people aged 55 and over will be vaccinated with the COVID-19 vaccine from the American pharmaceutical company Johnson & Johnson. This is the fourth COVID-19 vaccine to be licensed in France, after the products of Pfizer / BioNTech, Moderna and AstraZeneca. Meanwhile, to prevent the emergence of new variants of the SARS-CoV-2 virus, the French Ministry of the Interior decided that all passengers from Argentina, Brazil, Chile, India and South Africa would have to undergo quarantine. At the accommodation for 10 days, under the supervision of French police. Currently, health officials in all countries are encouraging the implementation of measures to be alert for the types of viruses with faster spread rates. Also on April 22, Belgian health officials announced the presence of the virus variant in India in this country. Specifically, the new variant was discovered in 20 nursing students from Paris (France) to Belgium in mid-April. The group with a total of 43 students was quarantined upon entry. Experts say the group was infected from a super infectious patient, possibly a member of the group, or from another passenger also on the trip from France to Belgium. A variant of the virus detected in India called B.1.617 has also appeared in several other countries such as the US, Australia, Israel and Singapore. Concerned about this variant, some countries, including the UK, applied a restriction on travel with India.

This has resulted in many countries that used to order large quantities of vaccines, but were unable to use them. And the liquidation of excess vaccine doses is becoming a new problem that causes these countries to “headache”. What is really happening According to the BBC, the cause comes from concerns about rare, and sometimes fatal, cases of blood clotting abnormality, after receiving even one dose of the AZ and J&J vaccines. . This concern is growing, especially among young people. The excess amount of Covid-19 vaccine is causing many countries to “headache”. Photo: AP Based on data from the British Drug Administration, for every 10 million people assumed to be vaccinated with the AZ vaccine, about 40 people develop abnormal blood clots, of which 10 are at risk of death. This proportion equates to the risk of dying from homicides or road accidents in the UK in 2018. That is why the Danish health authority decided to stop using the AZ vaccine in response to the “risk of serious side effects”. This decision means that the 2.4 million doses of unused AZ vaccine in Denmark are at risk of being recalled. South Africa also suspended the distribution of the vaccine, as it was found to be less effective against strains. The same goes for J&J’s single-dose Covid-19 vaccine. Until safety investigation and testing is completed, the vaccine will not be approved for use in the US, which has 100 million pre-ordered doses. Number of ‘in stock’ vaccines Although there are no global overview data, individual country data can provide an overview of the current status of vaccine oversupply. According to data from the Centers for Disease Control and Prevention (CDC), an average of more than 20% of vaccines in the United States are unused. However, some states also exceed this rate such as Alabama (37%), Alaska (35%), Vermont (27%) and North Carolina (24%). Similar circumstances are playing out in Europe, where several countries have enacted restrictions on AZ and J&J vaccination against older adults. Data from the European Center for Disease Control and Prevention (ECDP) shows that out of a total of 202,920 doses of new AZ vaccine received by Denmark on April 15, 150,671 doses were distributed for vaccination. Danish medical director Soeren Brostroem said the AZ vaccine recall was a “difficult” decision. Photo: EPA Find a liquidation solution In theory, countries can still sell or donate vaccines they no longer use to other countries. On April 15, Hans Kluge, European Director of the World Health Organization (WHO), said that Denmark is looking to do this. “I understand that the Danish Ministry of Foreign Affairs is ready or considering options to share the AstraZeneca vaccine with poorer countries,” Kluge said at a news conference. In the opposite direction, many neighboring countries with Denmark also offered to buy back. Prime Minister Ingrida Simonyte has offered to be ready to receive a large number of AZ vaccines with Denmark. Czech Interior Minister Jan Hamacek also said that he had instructed a diplomat to declare the country’s interest in “buying all AZ vaccines from Denmark”. However, Copenhagen has yet to comment or respond to these requests. In the meantime, the vaccines are still stored in cold storage without an appointment for use. Share to the world Currently, Covax is considered the most feasible way for many countries to distribute their surplus vaccines to the world. With a mission to share vaccines fairly between countries, regardless of rich and poor, Covax aims to deliver more than 2 billion doses to people in 190 countries by the end of 2021. Photo: Reuters Some developed countries also plan to distribute their own excess vaccines. For example, the UK, which owns about 450 million doses of vaccine, has pledged to fund most of the “surplus” vaccine source to poorer countries. More than 1 million doses of the AZ vaccine recalled by South Africa were distributed to 14 other African countries. While it is not yet specific when or how many doses of vaccine will be distributed, this suggests that at least for now, developed countries still have a responsibility to share excess vaccine. to the world, through programs like Covax. In response to the BBC, the representative of the Global Alliance on Vaccines and Immunization said: “With a limited supply of vaccines in the near future, doses of vaccines are donated from other countries. Surplus and equitable allocation through Covax will be the key solution, for equitable and rapid access to vaccines globally. We are talking to some high-income economies about their share of excess vaccines, and expect them to announce the deals soon. ” Vietnamese-English

The world has been getting COVID-19 vaccination for several months. Besides the hope that the COVID-19 pandemic will soon be controlled, there is no small concern with the fact that a series of new virus variants have appeared and are still appearing. It can be said that the global market is in the race between the vaccine and the unknown virus variants. The COVID-19 vaccine from Johnson & Johnson started being distributed in the US in early March amid dangerous spreading of the variants. Photo: GETTY IMAGES Many dangerous variations Virus strain means there is a mutation, changes in the genetic structure of the virus, causing the virus to change the way it works. In addition to the old virus strain, the world currently has many new variants such as B.1.1.7 (originated from England, has spread to more than 90 countries), B.1.351 from South Africa (has spread to more than 40 countries). , P1 and P2 from Brazil (has spread to 25 countries, some cases have been infected and recovered from being re-infected with variant P1), D614G from Europe, A.23.1 from Rwanda. In which the variant appeared from South Africa is said to be the most difficult to prevent and the most dangerous. Studies show that the vaccine strain B.1.351 of the vaccine from Pfizer / BioNTech and of AstraZeneca / Oxford is not as effective as the old vaccine. Clinical trials of vaccines by Johnson & Johnson and Novavax also showed that the ability to prevent this variant is not high. These variants – with a faster rate of spread, a higher risk of death, and an easier way to outdo existing vaccines – threaten efforts to contain the COVID-19 pandemic. And yet, the appearance of the variants also points to another concern: More dangerous variants will emerge in the future if the world fails to win the current race. The current pace of immunization globally is worryingly slow, especially in poor countries. It can be understood that even though rich countries vaccinate rapidly, new variants may emerge in poor countries that have not yet had adequate immunization coverage. Understanding these risks, vaccine developers are working hard to increase effectiveness in coping with variants. And the global health organizations are also making efforts to accelerate the speed of global distribution and vaccination. These are difficult times. This will be our toughest time to see which side wins. If we can hold on for another month or six, there’s a big difference. TS PETER HOTEZ , Rector of Baylor College of Tropical Medicine (USA) Vaccine firms’ efforts The Pfizer / BioNTech vaccines and Moderna’s vaccines (both doses) both use the mRNA molecule as the foundation. This molecule instructs the body to make a mutant protein found in the SARS-CoV-2 virus, which signals the immune system to fight off the mutant protein if encountered. The Oxford / AstraZeneca vaccine (two doses) uses a reprogrammed version of another virus, adenovirus, that uses the DNA encoding the mutant protein of SARS-CoV-2. The Johnson & Johnson vaccine (single dose) also uses adenovirus. With these two vaccine platforms, once they want to redirect to deal with new variants, developers will need to modify their DNA or mRNA codes. Fortunately, this can be done simply and quickly, but the disadvantage is that it will require expensive changes to the vaccine production process and more time to produce and distribute. Hoping to avoid these shortcomings, Pfizer is now considering the possibility of adding a third dose to the current two-dose regimen to reinforce the effectiveness of preventing new variants. Talk to the radio NBC News At the end of February, Pfizer chief executive Albert Bourla was confident that “the third dose will increase the antibody response 10 to 20 times”. Moderna is also working on the possibility of giving one-dose booster to the current two-dose regimen. In addition, at the end of February Moderna sent a version of the vaccine optimized to cope with the variant in South Africa to the US National Institutes of Health for further study. Meanwhile, Johnson & Johnson is confident its vaccine is resistant to many more variants because it is developed later than the above brands. Johnson & Johnson are also working on a two-dose vaccine (currently only available in one-dose version). Last week Pfizer announced that it would soon launch the trial of COVID-19, a positive news that gives further hope to quell the pandemic. Meanwhile according to the news agency Reuters Currently, many Asian countries are speeding up the distribution of AstraZeneca’s vaccine, after a period of concerns about the safety of the information that this vaccination causes thrombosis appeared in Europe. Earlier this week, many countries and territories in Asia activated vaccination. Some regional leaders are also vaccinated to reinforce confidence, including the Head of the Administration of Taiwan Institute – Mr. To Trinh Xuong, Prime Minister of Thailand Prayut Chan-o-cha. In Europe, after a short hiatus, many continental countries have also restored this vaccination. British Prime Minister Boris Johnson received the first dose last weekend and said “nothing strange”. The AstraZeneca vaccine is one of the few first available COVID-19 vaccines, available at a low cost and according to Reuters This vaccine will be at the heart of COVID-19 vaccination programs in most developing countries. The positive side of “vaccine diplomacy” Currently, the giants of vaccine COVID-19 (USA, China, India) are trying to expand distribution of vaccine globally. Compared to the US, the two countries India and China are more enthusiastic about implementing the campaign “vaccine diplomacy”. China has announced it will donate vaccines to 53 countries, and has already shipped millions of doses of its domestic vaccine to Asia, Africa and Latin America. When asked if the US could surpass China in “vaccine diplomacy” last week, the State Department spokesman did not respond. However, according to the news site The Hill The US is working with countries in the quartet group (India, Australia, Japan) to discuss providing vaccines to Asian countries to both stop the COVID-19 epidemic and as a counterbalance to China’s “vaccine diplomacy” campaign. National. Secretary of State Antony Blinken discussed this with three of their counterparts from February 18. During a meeting with G7 leaders last month, US President Joe Biden promised that the United States would donate 4 billion doses to the World Health Organization (WHO) Gavi vaccine alliance and possibly many more.

The overseas new crown vaccine “thrombus gate” continued to ferment. Following AstraZeneca, Johnson & Johnson’s vaccine was also urgently stopped.

On April 13, the U.S. Centers for Disease Control and Prevention (CDC) and the U.S. Food and Drug Administration (FDA) issued a joint statement stating that in view of the fact that the U.S. has reported 6 cases of “rare and severe” thrombosis after being vaccinated by Johnson & Johnson, It is recommended to suspend vaccination of Johnson & Johnson’s new crown vaccine.

In this regard, vaccine expert Tao Lina (Vaccines and Science) told the reporter of China Times that even if it is finally confirmed that the vaccines of AstraZeneca and Johnson & Johnson have caused rare blood clots, it is necessary to weigh the pros and cons before making a decision.

As the vaccines of AstraZeneca and Johnson & Johnson are both adenovirus vector vaccines, CanSino shares continue to fall sharply. From April 14th to 15th at noon, Cansino A shares reported 349.16 yuan per share, a cumulative decline of about 8% during this period; Hong Kong stocks reported 270.8 Hong Kong dollars per share, a cumulative decline of about 14% during the period.

Johnson & Johnson Vaccines Was Urgently Stopped by the U.S.

According to the official website of the FDA, Johnson & Johnson’s vaccine was approved for emergency use on February 27 for use by people over 18 years of age. It was developed by Johnson & Johnson’s Janssen Pharmaceuticals. This vaccine is an adenovirus vector vaccine. It only requires one dose. The most common side effects are pain at the injection site, headache, fatigue, muscle aches and nausea. Most of these side effects occur within 1-2 days after vaccination, and are mild to moderate and last for 1-2 days.

The above 6 cases of adverse reactions occurred during the vaccination process of more than 6.8 million doses of Johnson & Johnson vaccine, all women aged 18-48, who developed cerebral venous sinus thrombosis and thrombocytopenia at the same time 6 to 13 days after vaccination. This side effect is “extremely rare” and the treatment is different from common blood clots.

On April 14, the CDC’s Immunization Practice Advisory Committee met to discuss these cases, and the FDA has also begun investigating these cases. At present, it has not been confirmed that there is a clear causal relationship between rare thrombotic events and Johnson & Johnson’s new crown vaccine. The two agencies recommended that states suspend continued vaccination against Johnson & Johnson until the complete investigation process is over.

In response, Johnson & Johnson issued a statement on the 13th, saying: “We have been reviewing these cases with European drug regulatory agencies. We have decided to proactively postpone the promotion of the vaccine in Europe, and suspend all clinical trials of the new crown vaccine, and update the research. The guidance of the participants and the participants.”

Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said that the suspension of the Johnson & Johnson vaccine is out of cautious consideration, allowing relevant institutions to further understand the status of patients with adverse reactions and the mechanism of side effects. The probability of such side effects is extremely low, so those who have been vaccinated by Johnson & Johnson need not be anxious.

The health department recommends that people who experience severe headache, abdominal pain, leg pain, or shortness of breath within three weeks after receiving the Johnson & Johnson new crown vaccine should contact their healthcare provider.

At present, the suspension of Johnson & Johnson vaccination will not have a major impact on the progress of the new crown vaccination in the United States. Jeff Zienz, an expert on the US White House’s New Crown Epidemic Response Team, said that Johnson & Johnson vaccines account for less than 5% of the current US vaccination records. The US government is working with states and partners to help the Johnson & Johnson vaccines that have been booked. The patient should be rescheduled to receive Pfizer or Modena vaccine as soon as possible.

In fact, four days before the United States stopped Johnson & Johnson’s vaccination, the European Union has begun to review the safety of the vaccine. The vaccine was approved for conditional marketing in the EU in March, but has not yet been delivered. According to the plan, Johnson & Johnson will provide at least 200 million doses of the new crown vaccine to the EU within this year.

Following AstraZeneca’s footsteps?

It seems that Johnson & Johnson has followed in the footsteps of another multinational giant, AstraZeneca.

In March, due to the symptoms of bleeding, thrombosis and reduced platelet counts among medical staff in Denmark, Norway and other places after vaccination, nearly 20 countries including Germany, France, Denmark, Norway, Iceland, Italy, Thailand, Austria, etc. once called for a stop. Sleek vaccination.

On April 7, expert teams from the European Medicines Agency (EMA) and the World Health Organization (WTO) successively issued statements stating that the vaccine developed by AstraZeneca and the University of Oxford may be related to rare blood clots. The EMA Safety Committee (PRAC) believes that rare thrombosis with thrombocytopenia should be classified as a very rare side effect of the AstraZeneca vaccine. However, the overall benefits of the vaccine in preventing new coronary pneumonia outweigh the risk of side effects.

PRAC conducted an in-depth review of the 62 cases of cerebral venous sinus thrombosis and 24 cases of splenic vein thrombosis reported in the EU drug safety database as of March 22, 2021. Among them, 18 cases were fatal. These cases were mainly from the spontaneous reporting system of the EU and the United Kingdom. Approximately 25 million people have received the vaccine.

PRAC pointed out that thrombosis occurs in cerebral veins (cerebral venous sinus thrombosis) and abdominal veins (splenic vein thrombosis) and arteries, accompanied by low platelet levels and sometimes bleeding. So far, most of the reported cases have occurred in women under 60 years of age within 2 weeks of vaccination.

AstraZeneca said that it will update the vaccine product instructions and add information about the vaccine and “very rare” thrombosis on the new label. Together with the WTO and EMA, we are conducting unified observations on patients with symptoms after vaccination and conducting further research.

At present, many countries have announced adjustments to the AstraZeneca vaccination groups, including the United Kingdom, the Philippines, Australia, South Korea, Belgium, etc., but there are differences in age. The United Kingdom advises against vaccinating AstraZeneca for people under 30 years of age, Belgium suspends vaccinations for people 55 years of age and under, Australia suspends vaccinations for people under 50 years of age, and Spain, South Korea and the Philippines only for people over 60 years of age Get the vaccine.

Recently, the “New England Journal of Medicine” published two important studies at the same time, analyzing the symptoms of thrombosis and thrombocytopenia in patients after vaccination with AstraZeneca.

In the first study, the Norwegian research team reported that 5 cases of rare venous thrombosis and thrombocytopenia were found in more than 130,000 vaccinators. High levels of antibodies against PF4-polyanion complex were detected in the blood of all patients. This antibody can activate platelets, leading to abnormal formation of thrombus and a decrease in the number of free platelets.

In the second study, the German research team analyzed the clinical and blood test data of 11 patients who experienced thrombosis or thrombocytopenia after being vaccinated with AstraZeneca in Germany and Austria. Testing of patients’ blood samples also found high levels of antibody responses to PF4-heparin complex or PF4. Historical studies have shown that other factors besides heparin may also trigger symptoms very similar to heparin-induced thrombocytopenia.

China’s Cansino vaccine implicated

It is worth noting that the vaccines of Johnson & Johnson and AstraZeneca both follow the path of adenovirus vector technology. Now that one after another is involved in the “thrombus gate”, are other adenovirus vector vaccines still safe?

At present, in addition to Johnson & Johnson and AstraZeneca, the satellite 5 (Sputnik-V) developed by Russia, and the new crown vaccine developed by China’s Cansino Biotechnology Co., Ltd. also belong to the adenovirus vector technology path. However, according to public information, the adenovirus vectors used in these four vaccines are different. The AstraZeneca vaccine uses the chimpanzee adenovirus vector, the Johnson & Johnson vaccine is based on the Ad26 adenovirus vector, and the Cansino vaccine uses the Ad5 adenovirus as the carrier. The first dose of the Russian satellite 5 vaccine uses Ad26 as the carrier, and the second dose uses Ad5 as the carrier. Carrier.

Affected by this news, Cansino’s stock price plummeted, A shares fell by 13%, and H shares fell by 18%. CanSino Bio had to issue an emergency statement stating that the Ad5 vector used by the company’s new crown vaccine is a common adenovirus that infects humans, which is different from the adenovirus vector used by AstraZeneca and Johnson & Johnson vaccines. As of the 14th, about one million people vaccinated with Cansino vaccine have not received reports of serious adverse events related to thrombosis. After the company’s statement was issued, the decline in Cansino’s share price narrowed. As of the close, Cansino A shares closed at 356.20 yuan per share, the decline narrowed to 6%; the decline of Hong Kong stocks also narrowed to 8%.

CITIC Securities believes that this phenomenon has not been found among the millions of vaccinators of Cansino vaccine; this has not been found in the previous use of Ad5 in other vaccines and drugs; after all, Ad5 is a viral vector with a high infection rate in humans. It is different from AstraZeneca, Johnson & Johnson and Carrier, and the probability of thrombosis is very different.

So, is Ad5 adenovirus vector safer? Taolina said that there are some studies on the thrombocytopenia caused by adenoviral vectors, but these studies are based on the results of high-dose systemic therapeutic applications.

In September 2011, Yu Xiunan and other researchers from the First Affiliated Hospital of Harbin Medical University published an article “Research Progress in Adenovirus Type 5 and Thrombocytopenia” in the Journal of Modern Laboratory Medicine, which mentioned that thrombocytopenia Symptoms are a major side effect of high-dose systemic application of adenovirus as a vector for gene therapy of carriers. Adenovirus can bind to CAR receptors on platelets, and can also bind to integrin receptors on platelets. “Recent studies have found that adenovirus may cause activated platelets. Adenovirus-induced thrombocytopenia is considered to be dose-dependent, saturated and reversible, which is consistent with the ligand-receptor mechanism. There are multiple views on the mechanism.”

Regarding the Johnson & Johnson vaccine, “I’m still suspending the use and continuing to evaluate it, but compared to no vaccination, I am expressly willing to accept the adenovirus vector vaccine.” Taolina said.

AstraZeneca’s COVID-19 Vaccine. (Photo: VNA broadcast) Regarding the issue of vaccine supplies of the European Union (EU), on April 18, the European Commissioner for the internal market Thierry Breton left open the possibility that the EU could decide not to continue ordering. vaccine of AstraZeneca due to a later than agreed upon delivery. The EU initially ordered 120 doses of AstraZeneca vaccine for 27 member countries in the first quarter of 2021 and 180 million doses in the second quarter of 2021. However, so far AstraZeneca has only delivered 30 million doses and is expected to have only 70 million more doses in the next quarter. Mr. Breton affirmed that there is currently no certainty and the EU is still negotiating with AstraZeneca. However, he stressed that no matter what the decision is not due to medical or epidemiological reasons, and affirms that the AstraZeneca vaccine brings more benefits than risks. U] Previously, on April 16, French Industry Minister Agnes Pannier-Runacher also mentioned the possibility that the EU will not renew the contract with AstraZeneca and both. Johnson & Johnson in the year 2022. Some EU countries have stopped using the AstraZeneca vaccine due to concerns about the risk of side effects occurring thrombosis. However, most countries have resumed their AstraZeneca vaccination program after the European Drug Administration (EMA) confirmed the safety and effectiveness of the vaccine.

NDV-HXP-S is the first vaccine in clinical trials to use a new molecular design that is expected to produce more antibodies than current vaccines. With that, new vaccines could be made much easier than current vaccines. Low- and middle-income countries can either produce the NVD-HXP-S vaccine on their own or buy it back at low cost from neighboring countries. Photo: NY Times Existing vaccines from companies such as Pfizer and Johnson & Johnson must be made in specialized factories using ingredients that are difficult to buy. Meanwhile, the new vaccine can be produced from eggs. According to the NY Times, eggs are the raw material that produces billions of doses of flu vaccine each year in factories around the world. If the NDV-HXP-S vaccine is proven to be safe and effective, influenza vaccine manufacturers are capable of producing more than one billion doses of the vaccine each year. Low- and middle-income countries that are currently having trouble buying vaccines from richer countries can make NDV-HXP-S vaccines themselves or buy them at low cost from neighboring countries . “That was amazing. This is going to be the game changer, ”said Andrea Taylor, assistant director of the Center for Global Health Innovation at Duke University (USA). First, clinical trials have to determine that NDV-HXP-S is indeed effective in humans. The first phase of clinical trials will end in July, and the final phase will take a few months. However, animal trials have raised hope about the prospects of the new vaccine. The key to the Covid-19 vaccine The Covid-19 vaccine works by activating a natural immune mechanism in the human body. SARS-CoV-2 virus has a round shape and many spines surrounding the surface. These spikes are also known as ‘prickly proteins’, and they act as keys to help viruses enter cells. The vaccine will cause the body to produce resistance that helps to block these dendritic cells. However, injecting only mutant proteins into the body is not the best way to make vaccines because mutant proteins sometimes assume the wrong shape and prompt the immune system to produce the wrong antibodies. This happened long before the Covid-19 pandemic broke out. In 2015, another coronavirus appeared to cause Middle East Respiratory Syndrome (MERS). Jason McLellan, a biologist at the Geisel School of Medicine at Dartmouth College, and colleagues have begun building a MERS vaccine. Researchers want to use mutant protein surges as a target, but they have to take into account the fact that mutant protein is a shape-altering substance. When the protein is about to fuse with a cell, it changes from a tulip-like shape to a javelin-like shape. McLellan and colleagues have discovered a way to keep proteins locked in a tulip-like shape is to change 2 of the more than 1,000 building blocks in the protein into a compound called proline. The protein spike to the two new proline molecules is more likely to assume tulip shape called 2P. The researchers injected the 2P mutation into mice and found that the animal could easily fend off the MERS-CoV infection. Scientists have published research on this mutant protein boost, but received little public attention. By the end of 2019, the SARS-CoV-2 virus has appeared and spread around the world. McLellan and his colleagues got into action, designing the 2P mutant for SARS-CoV-2. Within days, Moderna used that information to make the Covid-19 vaccine. Other companies quickly followed suit, applying the 2P mutation to Covid-19 vaccine makers and starting clinical trials. All three vaccines licensed so far in the US, Johnson & Johnson, Moderna and Pfizer / BioNTech, use 2P. Other vaccine manufacturers are also using 2P in vaccine trials. Novavax has had strong results with 2P mutant hemp protein increases in clinical trials and is expected to apply to the Food and Drug Administration (FDA) for an emergency license within a few weeks. next. Eggs – the simple ingredient that makes up the vaccine The first wave of Covid-19 vaccine development required the use of specialized and expensive materials for its fabrication. Moderna’s RNA-based vaccines, for example, require genetic building blocks called nucleotides as well as fatty acids. These ingredients make up a vaccine produced in purpose-specific construction factories. Meanwhile, the production of the flu vaccine is based on just one study. Many countries have huge factories to produce low-cost flu vaccines, made up of eggs. The team at the PATH Center for Vaccine Innovation and Access wondered if scientists could create a cheap Covid-19 vaccine grown in chicken eggs. In this way, a vaccine factory for the flu can also produce Covid-19 vaccine. In New York (USA), a team of scientists at the Icahn School of Medicine in Mount Sinai already knew how to create such a vaccine using a bird virus called the harmless Newcastle virus. people. For years, scientists have been studying the Newcastle disease virus to create vaccines for a wide range of diseases. To develop the Ebola vaccine, for example, researchers added an Ebola gene to the unique Newcastle virus genome. Then, the scientists put the genetically modified virus into eggs, because this is a virus that causes disease in poultry, it multiplies rapidly in the eggs. Researchers have found that the Newcastle virus is prevented by Ebola proteins. Researchers at Mount Sinai have found that the NDV-HXP-S vaccine can protect mice well from disease. “I can say, this vaccine can protect all mice against the virus SARS-CoV-2. However, many people still do not understand the effects of this vaccine on humans, “said Peter Palese, lead researcher said. According to the NY Times, one egg can make 5-10 doses of the NDV-HXP-S vaccine, compared with just 1-2 doses of the flu vaccine. “We are very excited about this, because this could be a way of making a vaccine at low cost,” said Peter Palese. For some countries, the prospect of self-production of Covid-19 vaccine is highly desirable. However, Madhavi Sunder, an intellectual property expert at the Georgetown Law School, warns that the NDV-HXP-S vaccine will not help countries like Brazil get out of pandemic immediately when they are facing the tide. New Covid-19 translation wave. “We’re not talking about billions of doses of vaccine production. Instead, this strategy will be important for long-term vaccine production, not only for the Covid-19 epidemic but also for other possible pandemics in the future, ”Madhavi Sunder said.

COVID-19 vaccine from Johnson & Johnson. Photo: AFP / VNA On April 13, US federal health authorities recommended to suspend the use of Johnson & Johnson’s COVID-19 vaccine for “cautious” reasons, awaiting the results of investigating the possible link between the vaccination. this with thrombotic side effect. The Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC) are reviewing six cases of thrombosis following the vaccination. Meanwhile, according to Reuters, on April 15, US infectious disease expert Anthony Fauci hopes that US regulators will soon make a quick decision on resuming Johnson & Johnson’s vaccination, bringing the vaccine back. immunization program. The day before, the US CDC advisory committee postponed at least a week to vote on whether to resume use of the Johnson & Johnson vaccine to wait for more data on thrombotic risks. Mr. Fauci feared that the prolonged delay of the vaccine could affect people’s hesitancy. “I think we need to continue to emphasize that this is a very effective and usable vaccine that is very, very valuable in a global context,” he said. Following the US, some countries have made similar moves with the Johnson & Johnson vaccine
On April 13, the South African Ministry of Health announced it had suspended the use of the Johnson & Johnson vaccine in the country’s vaccination program, although South Africa has not received a report related to coagulation after 290,000 people in the country. has received the COVID-19 vaccine from the brands. Two weeks ago, South Africa licensed the use of vacicne Johnson & Johnson and so far only vaccinated this vaccine to health workers in the study framework. Before the above developments, Dutch Health Minister Hugo de Jonge said that the country has not decided whether to launch the Johnson & Johnson vaccine injection this week or not. He stated that the Netherlands will wait for information from the European Pharmaceutical Authority (EMA) before making a decision. In contrast, some countries continue to use the Johnson & Johnson vaccine. Belgium has said it will not stop the vaccination at this stage. Poland started to vaccinate Johnson & Johnson when the government confirmed that the benefits of the vaccine outweigh the risks. Meanwhile, Spanish officials have not received the notice of stopping the Johnson & Johnson vaccination. For its part, the World Health Organization (WHO) says it is monitoring global data of various reports to see if similar cases occur elsewhere, and it will take time. Time to evaluate vaccine data from Johnson & Johnson. Denmark completely discontinues the AstraZaneca vaccine; Thailand is still considered the mainstay Prime Minister of Thailand Prayut Chan-O-Cha (middle) was vaccinated against COVID-19 by AstraZeneca company in Bangkok, on March 16, 2021. Photo: AFP / VNA Before the Johnson & Johnson vaccine, the AstraZeneca vaccine was also in the same situation. The AstraZeneca vaccine is suspected of causing thrombosis, causing a series of European countries to suspend use, despite WHO recommendations. Recently, on April 14, Denmark became the first European country to permanently stop using the AstraZeneca vaccine due to concerns about rare blood clotting side effects. Denmark thinks that AstraZeneca’s vaccine may not be needed because it has managed the COVID-19 pandemic and may just depend on the vaccines from Pfizer and Moderna. Before that, from March 11, Denmark, along with Iceland and Norway, have suspended the use of this vaccine. Followed by a number of other European countries, including France, Germany and Italy. Federal Health Ministers and states in Germany unanimously recommend a second shot after getting the first shot with the AstraZeneca vaccine, under which one shot of the preparation is given to those under 60 years of age. This could be a second shot with another vaccine. In Bulgaria, Health Minister Kostadin Angelov also announced that the launch of AstraZeneca’s vaccine in the country could be stopped because people are not interested. The European Drug Administration – the European Union’s (EU) drug regulator – then recommended that countries continue to use vaccines as the benefits of vaccines far outweigh any potential risks. hidden from humans. Last week, the European pharmaceutical regulator listed clotting as an extremely rare side effect of the AstraZeneca vaccine. Some countries have started to re-use the vaccine after the suspension, but limited in the number of people vaccinated. As is the case in the UK, the country says it will offer another vaccine for people under the age of 30. While some countries are vaccinated with AstraZeneca, Thailand Health Minister Anutin Charnvirakul announced that the AstraZeneca vaccine will be the mainstay of the Southeast Asian country’s COVID-19 vaccination program. Mr. Anutin confirmed that Thailand has the expertise to closely monitor vaccine information and the decision is based on science. Thailand’s vaccination campaign mainly relies on domestically produced AstraZeneca vaccine and 2 million doses of Chinese vaccine to vaccinate about 35 million people, equivalent to 50% of the population – Thailand’s goal. must be reached by the end of 2021. Along with Thailand, Korea has decided to continue to vaccinate AstraZeneca for those who qualify. People younger than 30 years of age have not yet received the vaccine because the risk of blood clots outweighs the benefit of the vaccination. Continued reassurance and investigation of coagulation phenomenon after vaccination Health care workers give COVID-19 vaccine to people in Llanelli, South Wales (UK), April 9, 2021. Photo: AFP / VNA While countries are moving differently with the Johnson & Johnson and AstraZeneca vaccines, WHO continues to assert the benefits of COVID-19 vaccination. On April 15, WHO Director in Europe Hans Kluge reaffirmed that the benefits of the AstraZeneca vaccine outweigh the risks. “Make it clear that there is no doubt that the AstraZeneca vaccine is effective in reducing hospital admissions for COVID-19 and preventing severe illness that leads to death. The WHO has recommended this vaccine as soon as possible,” he said. as possible for adults to increase resistance to the SARS-CoV-2 virus “. WHO officials also pointed out that out of the 200 million people who got the AstraZeneca vaccine, there are only a few rare cases of a blood clotting disorder. He emphasized that the risk of blood clots in patients with COVID-19 is much higher than in those receiving the AstraZeneca vaccine. A study by scientists at the University of Oxford UK showed that COVID-19 patients have a higher risk of developing blood clots in the brain than those vaccinated against the disease. Data from over 500,000 patients with COVID-19 show that blood clotting occurs at an incidence of 39 out of 1,000,000 patients. Of the more than 480,000 people who received the COVID-19 vaccine made by BioNTech / Pfizer or Moderna, the incidence of coagulation was 4 / 1,000,000, while the rate was slightly higher for those receiving the vaccine. AstraZeneca – about 5 / 1,000,000 after the first injection. After the coagulation incident with the Johnson & Johnson and AstraZeneca vaccines, the researchers found that this rare side effect only occurs with vaccines using adeno virus vector technology (the virus that causes the common cold). There has been no record of coagulation in people who received the vaccine using other technologies from Pfizer and Moderna. However, the link between the technology using adeno virus vectors and coagulation is only a simple guess, there is no evidence. Russian vaccine has not caused any blood clotting cases and is increasingly “expensive”. Vaccine Sputnik V in Moscow, Russia. Photo: AFP / VNA When Western countries investigated blood clotting side effects, the Gamaleya Research Institute – which develops the Russian vaccine Sputnik V – said the vaccine has not caused any adverse reactions related to blood clotting. According to the Gamaleya Institute, there is no reason to equate the safety of the Johnson & Johnson, AstraZeneca vaccines with Sputnik V. All three of these vaccines are vector-based, using the adeno virus to deliver the protein of SARS-CoV- 2 into human cells, helping to stimulate the immune system’s response. However, all three manufacturers use different structures and technologies in vaccine formulation. Iran is the latest country to order Russian vaccines. Iranian Ambassador to Russia Kazem Jalali confirmed that the contract to buy 60 million doses of Sputnik V has been signed and completed, enough to give 2 doses to 30 million people. Ambassador Kazem Jalali also announced that Iran will receive the vaccine by the end of 2021. Russia is also transferring technology to produce this vaccine to a number of countries. Most recently, the Korean company ISU Abxis on April 15 announced an agreement with the Russian Direct Investment Fund (RDIF) on the technology transfer and production of Russia’s Sputnik V vaccine for Korean companies. . It is expected that the production of vaccine trials will soon be deployed at a facility in Yongin, south of Seoul. The Russian Sputnik V vaccine is the second most popular vaccine in the world approved for use by national pharmaceutical regulators.

The US pharmaceutical company Johnson & Johnson is postponing the launch of its vaccine in Europe. Reports of sinus vein thrombosis have been received and the decision has therefore been made to delay, the company said. The cases would now be investigated with experts and the authorities. The US health authority CDC and the FDA had previously recommended a temporary suspension of vaccinations with the Johnson & Johnson active ingredient. Six people in the US were diagnosed with sinus vein thrombosis between six and 13 days after vaccination, the authorities said in a joint statement. In three cases, thrombocytopenia, i.e. a lack of blood platelets, also occurred. They are women between the ages of 18 and 48 years.

Inoculated more than 6.8 million doses

According to the authorities, more than 6.8 million doses of the Johnson & Johnson vaccine have been administered in the United States to date. The vaccine, of which only one dose is sufficient for vaccination protection, received US approval at the end of February. The now recommended suspension of vaccinations is a precautionary measure until exact results are available, said the CDC and FDA.

No decision for Germany

A spokesman for the federal health department said they had not yet decided how to proceed after the US warnings. “We always take such warnings seriously and follow them up.” The spokesman also referred to the responsibility of the Paul Ehrlich Institute. The vaccine from Johnson & Johnson was also approved in the EU in mid-March, but, unlike in the USA, is not yet in use here. The EU Commission assumes that the vaccine will be delivered to the EU next week. A total of 55 million cans are to be delivered in the second quarter, a good ten million of them to Germany. The Johnson & Johnson vaccine is the second corona vaccine that is suspected to be associated with the occurrence of sinus vein thrombosis. Previously, some countries had temporarily suspended vaccinations with the AstraZeneca vaccine, including Germany.

US President Joe Biden speaks at the White House on April 14. Photo: Rex

Citing the research results of the Pew Research Center, the British newspaper Guardian reported that President Biden has received a credit rating of 59%.

Meanwhile, at the same time, predecessor Donald Trump received only 39% and former President Barack Obama received a 61% credit rating.

With the migration crisis on the southern border acting as an early test of President Biden’s capabilities, the American people perceive this as a very serious problem, even overcoming. COVID-19 translation at the present time.

Previously, in a Pew study in June 2020, 58% of respondents said that the COVID-19 pandemic was at the top of the list of concern. In the latest poll, that number has fallen to 47% as more people vaccinate and states reopen.

Pew interviewed 5,109 adults in the US in April 2021 for this poll. About 72% of participants rated the Biden administration’s vaccine implementation program as good and extremely good. Meanwhile, 67% of the respondents supported the COVID-19 support package and 36% answered “fully support”.

The probe was conducted before Washington announced a suspension of the Johnson & Johnson COVID-19 vaccine.

According to the Daily Mail, Mr. Johnson, ex-wife Marina Wheeler bought the house in 2003 for £ 690,000. Currently the house is worth about 1.2 million pounds. The house has a minimalist décor with white walls and wooden floors.

The new tenants will own a house about 288 square meters with 4 bedrooms. On campus there is an outdoor swimming pool and a small house with kitchen and fireplace.

British Prime Minister Johnson rents the house. (Photo: RIA)

British authorities said Prime Minister Johnson and his family could not stay in the property because of confidentiality principles under British Government regulations, forcing him to live in the Chequers mansion.

Traditionally, the country mansion that the incumbent prime minister stayed, rested on weekends and hosted international guests was the Chequers Palace, located on the 600-hectare grassland and forest in Buckinghamshire.

Mr. Johnson was not the first British Prime Minister to rent out his home when he moved to 10 Downing Street.

In 2010, former Prime Minister David Cameron also rented a house in Notting Hill worth 2.7 million pounds for about 6,000 pounds a month. And former Prime Minister Theresa May also rents out a London property, reports show she earns £ 10,000 a month.

In November 2019, Mr. Johnson sold the house in the north of London for £ 3.75 million (more than $ 4.6 million). The house used to be the home of Mr. Johnson with his second wife, Marina Wheeler, before the couple announced their divorce in September 2018. This five-story house was bought by Prime Minister Johnson in 2005 for nearly $ 2.4 million. The house is designed according to traditional architecture, has an area of ​​more than 306 m2 with 4 bedrooms, 3 bathrooms.

In March, British Prime Minister Boris Johnson wants to set up a charity to pay for the costly renovation of his home. The former work was overseen by the politician’s fiancé, Carrie Symonds – she has been unable to control her expenses, putting her future husband in a difficult situation.

Renovating an apartment on Downing Street in London costs “tens, tens of thousands of pounds”. In another conversation Mr. Johnson complained that the cost of repairs amounted to “more than a hundred thousand”.

To overcome this situation, Mr. Johnson decided to set up a charity that will receive funding to survive as a cultural heritage fund. Establishment application is being prepared. The head of the fund will be Baron David Brownlow, a millionaire and former Vice President of the Conservative Party of England.

Before that, in July 2019, Boris Johnson became the first British Prime Minister in history to live with an unmarried woman at the Prime Minister’s Palace at 10 Downing Street.

In April 2020, Prime Minister Johnson’s fiancé, Carrie Symonds, gave birth to a baby boy at a NHS National Health System hospital in London.

Some pictures of the British Prime Minister’s house for rent:

(Photo: The Image Barn)

Now, more than anyone, Americans feel very clearly that the lion has awakened and with his endless claws and ambitions, gradually from partner to rival of America. Mr. Joe Biden has chosen a different method from his predecessor: re-establishing alliances to control this ferocious “lion” has just awakened.

That’s exactly what President Biden’s administration is doing. Rotate the shaft to Europe; promoting the actual formation of the US – Japan – Australia – India “Diamond Four” mechanism. And strengthening 3-way relations with 2 partners, 2 top US allies in Northeast Asia: Japan, South Korea.

An offer cannot be refused

That is a relationship with many ups and downs spanning many decades in history.

In the early 1960s, when China had just acquired nuclear weapons and the Vietnam War was on the rise, President Johnson’s administration sought to promote relations with Japan. and Korea aimed to counter the communist movement in Asia. But, in order to reinforce this triangular relationship, it was the Johnson administration’s job at the time to “repair” the bilateral relationship between Japan and Korea, which had continued to tense after grievances in the past. World War 2.

Mr. Joe Biden has different methods from his predecessor. Photo: LG

The US had in hand a “trump card” to solve this dilemma: the superior military and economic strength at that time. Who pays, he or she has the right to order music! While Japan and South Korea continued negotiations that lasted more than 13 years, since 1951, aimed at normalizing bilateral relations, American diplomats have delivered a fairly simple message: what if Japan Japan and South Korea have established a friendly relationship, the US will continue to provide both military and economic support for both partners.

Simply put, it is an irrefutable offer! On June 22, 1965, at the Prime Minister’s Palace in Tokyo, the representatives of Japan and Korea signed the Treaty on Basic Relations between Japan and Korea, often referred to as the Japan-Korea Treaty. This treaty provided the basic foundation for restoring diplomatic relations between Korea and Japan, which had been interrupted since 1945.

By the 1980s, the administration of US President Ronald Reagan continued the policy direction of promoting relations between Japan and South Korea. With the encouragement of the United States, South Korean President Choon Do-hwan and Japanese Prime Minister Nakasone Yasuhiro held the first summit in 1983 and 1984. The United States also pledged to ensure security for Korea. , reassessed strong support for Japan, while calling on Tokyo to play a greater role in ensuring security in Asia.

By the late 1990s, the US began a new step in its relationship with two allies in Northeast Asia: the US – Japan – Korea triangle relationship. To foster this relationship, a Tripartite Monitoring and Cooperation Group (TCOG) has been formed as well as the implementation of the “Perry Process” (named US Secretary of Defense William Perry), which is the to the expert level to help policymakers of the three sides have conditions to discuss and exchange to strengthen cooperation between the US and Japan and South Korea …

“Thorn” in a 3-way game

However, the US will have to make a lot more effort if Biden’s policy of strengthening relations with Northeast Asian allies will be effective, because the Japan-Korea relationship has recently shown signs of developing. Fierce disputes, no signs of cooling down.

For more than three decades after the signing of the Japan-Korea Treaty, the two sides continued to argue over different interpretations of the treaty, which exempted Japan from any compensation for the period of its occupation. during World War 2.

In 2018, the Supreme Court of Korea suddenly ruled that Japanese companies must compensate victims of forced labor during the war. After this controversial ruling, the relationship between the two sides quickly turned in a bad way. Both Seoul and Tokyo are excluded from the list of most favored nation states in trade relations. While Tokyo imposed restrictions on the export of key raw materials on Korea’s large-scale semiconductor industry and many other items, a nationwide boycott campaign took place. items made in Japan. Japanese businesses are also the subject of anti-countermeasure campaigns in Korea …

The dispute between the two sides culminated when in August 2019, Seoul announced that it was likely to withdraw from the Treaty on Important Information Sharing with Tokyo, which was signed in 2016; South Korea will only continue to cooperate with Japan in military information, through a trilateral information-sharing agreement, in which the US plays an intermediary role.

This action threatened the US-Japan-Korea alliance structure in the context of Northeast Asia geopolitics frequently “red alert” due to tensions on the Korean Peninsula. However, just a few hours before the Japan Intelligence Sharing Treaty expires, Seoul decided to extend the treaty, a move that made the United States relieved, relieved of its thousands of pounds that threatened to destroy it. broken US – Japan – Korea triangular relations.

Throughout 2020, the bilateral relationship between Korea and Japan did not improve significantly. Most recently, the Korean Defense White Paper announced in February 2021 no longer calls Japan “partner”, a worrying signal for the relationship between the two sides. In the context of the COVID-19 epidemic raging around the world, travel restrictions have further reduced opportunities for exchanges between people of the two countries, making the ability to restore Japan-Korea relations very difficult. towel.

Japan remains an economic powerhouse. Photo: LG

The currency is the currency ahead of Wisdom

During his four years in the White House, Mr. Trump has repeatedly questioned the value of allies in Northeast Asia, repeatedly debating the costs of maintaining US troops in both Korea and Japan. Copy. Those moves have undermined the US’s ability to assume the unwritten role of being a (key) party building a bridge between Seoul and Tokyo. This leads to the fact that the US – Japan – Korea triangular relationship has fallen into the bleakest situation in the last months of the Trump term.

Aware of the damage caused by his predecessor, the Biden administration seeks to reorganize the trilateral alliance relationship. It is important not to let either partner feel the US is biased towards the other.

However, it is obvious that due to the different geographical location, history, political regime as well as the size of the economies of each party, the value of each Northeast Asian ally to the United States is also. different.

Outperformed by China (to become the second largest economy in the world), Japan remains an economic powerhouse. But, this economy is increasingly dependent on Chinese markets, capital sources and production chains. Therefore, Japan is careful when choosing its position, ensuring to gain the greatest benefits in the context of the fierce Sino-US confrontation.

Tokyo’s optimal choice is to build a relationship just enough with the US to avoid falling into a passive position in the Sino-Japanese relationship, as a bargaining chip with China; while maintaining its role as a trusted US ally to deal with the security challenges that have recently emerged on the Korean Peninsula.

Compared to Japan, South Korea is more dependent on the US for the military but more on China economically. The US is the only ally, and China is Seoul’s biggest trading partner. Korea cannot and does not want to have to choose between either party. Maintaining a relatively neutral position between the US and China is also a sensible choice for Seoul.

In order to serve the strategy of rebuilding allied relations in Northeast Asia, not only actively mediating the difficult relationship between Japan and South Korea, the US must also actively involve Japan. and South Korea is back in a trajectory that is allied with America itself. At the end of February, the US and Japan signed a cost-sharing agreement for the US military stationed in Japan. By early March, the US reached an agreement with South Korea to sign the XI Special Bilateral Military Cost-Sharing Agreement (SMA) for a period of six years.

These are the economic levers that were used decades ago and they are still in effect today.

The money (of the US) is the smart money!

U.S. halts use of Johnson / Johnson vaccine

The implementation of johnson&johnson’s (J&J)one-dose Covid-19 vaccine was halted on April 13 when regulators announced they were reviewing rare cases of blood clots after receiving it. The move could prompt thousands of people expected to get the J&J vaccine this week to find an alternative.

The Food and Drug Administration (FDA) and the U.S. Centers for Disease Control and Prevention (CDC) both recommend halting the distribution of the J&J vaccine after recording 6 cases of cerebral vein sinus thrombosis (CVST).

Illustration: Reuters

Symptoms are noted in women between the ages of 18-48 and appear 6-13 days after the J&J. vaccine injection. “Among cases of coaalysis in the U.S., one person has died and one patient is in critical condition,” said Peter Marks, head of the FDA’s Center for Biological Research and Evaluation.

However, stopping the use of the J&J vaccine in the US when there are only a few cases of blood clots has raised questions about over-reactions.

Speaking at the White House on April 13, Dr. Anthony Fauci, Director of the National Institute of Allergy and Infectious Diseases, said that the CDC and FDA have acted “with extreme caution” and stressed that the decision to recommend stopping the use of the J&J vaccine is only temporary.

“I don’t think they made the decision in a hurry,” Mr. Fauci said.

Despite this, the move left those planning to get the J&J vaccine confused and raised concerns that it could cause hesitation over covid-19 vaccination.

Earlier, 15 million J&J vaccines were damaged due to production errors at a factory. In Colorado, three mass vaccination points stopped using the J&J vaccine last week after 11 people reported symptoms of nausea and dizziness after receiving the vaccine.

For regulators, halting the use of the J&J vaccine has made it difficult to meet the urgent need for vaccines during the pandemic. When investigating the issue, U.S. officials must also try to maintain public confidence in the vaccination program. The suspension of J&J vaccination shows that regulators are taking potential issues seriously, but if they can’t find an answer yet, it could make people more concerned about vaccinations.

Link between J&J vaccine and cerebral vein sinus thrombosis

Cerebral vein sinus thrombosis (CVST) is a condition in which blood clots are formed in the veins and sinuses of the brain. This is a rare form of a stroke. In the general population, this symptom occurs in about 5 out of 1 million people. Symptoms of CVST include headache, blurred vision, convulsions, and loss of body control.

However, there are a number of factors that cause regulators to pay attention to cases of CVST after a single dose of J&J. Mr. Marks explained that, patients with blood clots also have tinglet reduction, the condition of tinglets in the blood decreases to very low levels, leading to bleeding and bruising. The combination of blood clots and low tinglets prevents patients from using common anti-coaculation treatments such as heparin, a blood thinner. That’s why health officials want to halt J&J.J. vaccinations until concerns can be investigated and give new guidance if necessary.

In addition, another factor is the cases of blood clots that occur in young women, who usually do not face a high risk of suffering from this disease.

The suspension of the J&J vaccine has been reminiscent of many European countries suspending all or part of the Covid-19 AstraZeneca vaccination program due to fears of blood clots. In March, the European Medicines Regulator (EMA) halted distribution of the AstraZeneca vaccine before allowing it to continue. Later, regulators concluded the AstraZeneca vaccine did not increase the risk of blood clots.

“This is a safe and effective vaccine. The benefits of vaccines in protecting people from the risk of dying and hospitalization from Covid-19 are far greater than the possible risks,” EMA Executive Director Emer Cooke said at a press conference in March.

Both the AstraZeneca vaccine and the Johnson /Johnson vaccine are based on modified adenovirus vectors. Adenovirus is a separate virus designed to provide DNA instructions to cellsto make the mutable protein of SARS-CoV-2, the virus that causes Covid-19.

Nearly 7 million people in the U.S. who have been vaccinated with the J&J. Vaccine AstraZeneca are still under review and have not yet begun distribution in the U.S., even though the country’s government has purchased millions of doses of the vaccine.

The link between the J&J vaccine and symptoms of cerebral vein sinus thrombosis has not yet been clarified, but Vox has made several assumptions.

“Mutant proteins are produced using instructions from vaccines,” said Robert Brodsky, Director of hematological division at Johns Hopkins University. In some cases, mutating proteins can trigger the response of the immune system. That immune response can also damage the tinglets, causing symptoms such as blood clots.

In addition, if a spike in a protein can trigger this reaction, it is likely that the virus is intact that can also activate CVST in vulnerable people.

Rare complications that create major public health challenges

The Covid-19 vaccine has been tested on tens of thousands of people in clinical trials, and all three licensed vaccines in the U.S., Moderna, Pfizer/BioNTech, and Johnson & Johnson have all been proven safe, with levels of side effects being mild to medium.

Health workers prepare J&j’s Covid-19 vaccine shots in Detroit on April 12. Photo: AP

But as the number of people taking part in vaccine trials increased from thousands to millions, rare complications began to appear.

That happened to Pfizer/BioNTech after the vaccine was distributed to the market. Some people after vaccination experience a severe allergic reaction to the Pfizer vaccine. Similar problems also appeared with the Moderna vaccine. In January, the CDC estimated that the rate of allergic reactions to the Pfizer/BioNTech vaccine was 11.1 per 1 million vaccinations, while the rate of the Moderna vaccine was 2.5 per 1 million vaccinations.

Health officials have revised the vaccination process to screen people with a history of severe allergies. They also asked the person after vaccination to stay for 15 minutes for monitoring, as most allergic reactions occur during that time period.

Regulators can add screening criteria for people at higher risk for blood clots before getting the J&J vaccine.

It’s too early to say whether regulators will do the right thing when it comes to halting J&J vaccinations. Studying potential vaccine issues can boost people’s confidence in vaccinations, but can also cause confusion and fear of complications, making more people more vigilant.

What about those who have received the J&J vaccine?

Dr Fauci said that, for those who had received the J&J vaccine more than a month ago, they didn’t need to worry. However, those who have recently received the J&J vaccine and begin to have symptoms associated with cerebral sinus thrombosis should inform their doctor. “6-13 days after vaccination will be the time of symptoms,” Mr Fauci said.

AstraZeneca’s COVID-19 vaccine. Photo: AFP/TTXVN

According to the Ministry of Health, the man was injected with a vaccine produced at India’s Serum Institute. The patient has returned home and is in the process of recovering.

Earlier, Canada limited AstraZeneca’s vaccine use to people over the age of 55 due to concerns about the rare reaction. The above information is the latest challenge for vaccination in Canada.

In addition, Health Canada confirmed that it is in discussions with Johnson & Johnson about the possibility of a COVID-19 vaccine. The department has asked Johnson /Johnson for information on any cases of post-injection blood clots. The agency is also working with the U.S. Food and Drug Administration (FDA) and other international agencies on the issue.

Although Canada has licensed Johnson&Johnson’s vaccine, the vaccines ordered will not be shipped until the end of April. Canada is expected to get enough vaccines so that by the end of June, each citizen can get one shot. However, the rate of spread of the new variants of the SARS-CoV-2 virus is surpassing the progress of vaccination in the country.

The number of new cases in the last week has increased by 33%, while the number of new daily infections is at more than 8,100, equivalent to the peak of the second wave of outbreaks earlier this year. Canadian Prime Minister Justin Trudeau warned more dangerous new variations were spreading rapidly and threatened progress had been made.

According to statistics worldometers.info, Canada has a total of over 1 million infections and over 23,000 deaths from COVID-19.

* Meanwhile, Australia announced that it will send Trade Minister Dan Tehan to Europe on April 15 amid reports that it has ordered more than 3 million doses of AstraZeneca’s vaccine made in the European Union (EU) but has not received the goods.

Under the plan, Minister Tehan will have dialogues with his German, French and EU colleagues to discuss eu production and export limits on AstraZeneca’s vaccines.

Australia is one of the countries that succeeds in controlling the COVID-19 epidemic. Since the outbreak, the country has recorded nearly 30,000 cases. However, Australia is currently behind in its vaccination campaign. As of April 11, Australia had only vaccinated nearly 1.2 million people, despite a pledge by the end of March to vaccinate 4 million people.

The Australian government believes that the EU’s non-delivery of the vaccines it ordered by AstraZeneca was the cause of the delay in the vaccination program, but state authorities pointed out that the distribution of vaccines to health facilities also contributed to this situation.

Under pressure from public opinion, Australian Prime Minister Scott Morrison said he would convene a cabinet meeting twice a week with state and territory leaders until the issue was resolved and put the vaccination program back on track.

Australia intends to vaccinate the majority of the population with AstraZeneca’s vaccine, which has imports from Europe and domestic production, while waiting for supplies from Pfizer and Novavax. The Australian government recently admitted it may not meet its target for COVID-19 vaccination for all residents next October due to import delays and new concerns about vaccine side effects.

* In Ireland, Health Minister Stephen Donnelly said the country is considering extending the vaccination period between Pfizer/BioNTech’s two doses to more than 4 weeks to maintain the vaccination progress, amid concerns that other vaccines such as AstraZeneca and Johnson /Johnson are being restricted from use due to safety risks.

In Russia, President Vladimir Putin confirmed he had given two shots against COVID-19. Speaking on television, Mr Putin expressed hope people would do the same to take care of themselves and their loved ones.

On March 23, President Putin received his first shot of the COVID-19 vaccine.

The Kremlin did not specify the type of vaccine the Russian President was vaccinated against, but insisted it was among three Russian-developed vaccines including Sputnik V, EpiVacCorona and CoviVac. In the interview, Mr Putin said he had suffered minor side effects such as muscle pain after his first injection but did not have a fever.