In 2001, the National Optoelectronics Industry Base settled in Wuhan, and Wuhan·China Optics Valley was born. Sitting on the technical advantages of optical communication, Wuhan took the lead in implementing the pilot project of “fiber-to-the-home and three-network integration” in the country, and then promoted it to the whole country, so that the people of the country can share the smooth travel of the network. In 2016, YOFC’s three main businesses of preform, optical fiber and optical cable all ranked first in the world. In the past 30 years, YOFC has produced nearly 700 million core kilometers of optical fibers, which are connected end to end, enough to pull the shortest distance from the Earth to Mars 6 back and forth. In recent years, cloud computing, big data, mobile Internet, and Internet of Things applications have rapidly emerged. How to solve the problem of “blowout growth” of network data flow has become a high ground for competition in the global information and communication field. As the leader of my country’s optical communication technology, China Information Technology Group has continued to make major technological breakthroughs in the field of “ultra-large capacity, ultra-high speed, and ultra-long distance” optical communication transmission. In 2017, they achieved 13.5 billion simultaneous calls on a single fiber. Today, they have achieved a fiber that can accommodate 30 billion people at the same time, leading the way. After years of cultivation, Hubei Province has a batch of “new technologies” grown from “root technologies”. It owns head technology companies such as China Xinke, Raycus Laser, Yangtze River Storage, and Renfu Pharmaceutical. They have provoked the important task of innovation in “optical core screen terminal network”, “life health” and “biological breeding”, and are making great strides towards the future. “Deep roots can make leaves grow stronger”, the person in charge of Hubei Provincial Science and Technology Department stated that only by accelerating the cultivation of “root technologies” and “new technologies” with strong vitality can the construction of Hubei be a science and technology province and continue to inject new momentum into Hubei’s high-quality development. More news: What is root technology? Root technology refers to a common technology that has a significant impact on multiple industries at the same time, and its characteristic is that it spans all walks of life. Measured by root technology and root industry standards, experts believe that the nine aspects of the Internet of Things, 5G networks, AI, fusion energy, 3D printing, gene editing, femtosecond lasers, quantum computing, and bioengineering are now and for a long time in the future. Root industry. Source: Photo courtesy of interviewees of Science and Technology Daily Editor: Zhang Shuang Review: Yue Liang Final review: He Yi

However, there is so much information about implantation that Hang does not know how to choose. In the cutlery world group, Mr. Nguyen C. shared about collagen-only products imported from Korea and most of the customers who buy these products are spas. Students only need to register for a period of time to be able to stretch threads for customers. Assoc. Dr. BS. Do Quang Hung, General Secretary of the Ho Chi Minh City Plastic Surgery Association, said that currently, beauty stretch marks are applied a lot in spas. Assoc. Hung himself has received many cases of complications when thread tensioning. Typically, a 41-year-old female patient has just called for help because of complications of facial pain and inflammation in the surgical area due to a facelift with only a private cosmetic clinic. According to the patient’s account, because she wanted to look younger, she went to have a skin tightening on her temples at a beauty salon in District 3, Ho Chi Minh City. After suffering hundreds of needles, but a month later, she still felt pain in both temples, so she went to Dr. Hung to ask for help. Doctor Hung had to surgically remove her temporal skin due to festering complications. Stretch only beauty. According to master, specialist doctor II Nguyen Minh Quang – Deputy Head of the Department of Research and Application of Stem Cell Technology, National Hospital of Dermatology, stretching is a rather popular beauty method. However, when looking at the image provided by the reporter, Dr. Quang was not clear about how the implant was done. “The blue procedure glove does not understand what it is?, the essence of the word “collagen thread stretch” is wrong. It is a marketing language that actually “stretches only to increase collagen production” – Dr. Minh said. According to Dr. Quang, many facilities now advertise stretch only with beautiful words and in those establishments, almost the people who perform them are not doctors. Most are spas with no technical safety procedures, just unlicensed, floating items. This method is considered a minimally invasive method. Similar to using fillers such as fillers, toxin are methods that are considered to change the structure of skin tissue, thereby creating obvious cosmetic effects. Before performing this measure, it is necessary to have an evaluation by a plastic surgeon and a cosmetic dermatology doctor to see if it is suitable for the indications. If it is appropriate, the doctors will plan the treatment, then proceed to perform this technique. This is a quite popular cosmetic method at home and abroad, has been applied for about 7-8 years in Vietnam, in which it has emerged again for a few years now. With thread material, people currently use 2 types of thread, which are slow-draining threads (only 24k gold and standards PDO, PLLA, PLC, catgut). For this thread, when entering the skin tissue, there will be a supporting effect. At the same time then only this will dissipate in the skin organization. The process that exists in the skin will stimulate the production of collagen and elastin, thereby helping to rejuvenate the skin, while limiting the formation of wrinkles … Or in some cases, the thread is used for reducing fat, tightening the biceps, abdomen, etc. Depending on the material, the time spent can only be from 6 months to several years. Stretching is also contraindicated in some cases because of an allergy to the above thread materials,… When there is a need to stretch threads, it is best for customers to go to reputable medical facilities for advice before implementation.

丨This article was originally created by Xiao Chen Tea

丨First published on Sohu: Xiaochen Tea

丨Author: Village Girl Chen

“1”

Eat barbecue with the customer service girl.

As usual, I took a pack of first-class white peonies, went to the barbecue restaurant, asked the store for a large glass pot of boiling water, poured the peonies into it, and drank it to understand that it was greasy and relieved of anger.

She said that she wanted to get the silver needle, but the tea was gone.

The silver needle tea is gone?

Yes, the silver needles have sold so well this year.

“Why do so many people fall in love with Yinzhen all of a sudden?” Village girl Chen remembered the scene of people shaking their heads when they heard of Baihao Yinzhen three or four years ago. What happened in this?

The customer service girl ate the grilled fish and explained that the customers I met were all because they were not short of money. As soon as they heard that Baihao Silver Needle was the most expensive in white tea, they desperately bought it.

Village girl Chen Nao made up this picture, it was indeed a bit beautiful.

Buying tea only picks the expensive ones, this is the waywardness of the rich.

But buying Baihao silver needles blindly like this is obviously inappropriate.

“2”

The price of Baihao Silver Needle this year is extremely expensive.

So in fact, the tea shopkeepers didn’t have many silver needles in their hands-who has so much real money in the goods?

They are still in the tea factory.

Especially in the context of the reduction in white peony production this year and the increase in silver needle production, tea factories of all sizes have placed a large number of white peony silver needles in their hands.

Do not believe? You can go to the tea area for a walk. See if the tea factory owners sell Baihao Silver Needles as soon as they come up? Or although it is not ranked first, but after drinking a few teas, the main recommendation is still silver needles.

Moreover, the main focus is still the “function card.”

At the moment of the epidemic, it looks like an effect card, which is the best card to play, and it is unsatisfactory.

As if to mention the effect, everyone flocked to it, no matter what, they bought it with their eyes closed.

But in fact, the owner of the tea factory pushes the silver needles most of the time to solve the financial pressure-the tea green money has been paid to the tea farmers, and the tea shopkeepers think that the silver needles are expensive and refuse to purchase more, so many silver needles finished tea piles. In the warehouse, how will the survival of this factory be maintained before it becomes realised a day?

As a result, the individual tourists who went to Chashan to find tea this year became the first eye-catching leeks.

Tea friends who went to Chashan to find tea, did you hear the sound of sharpening your knives while you were sitting in the lobby drinking tea?

“3”

Actually, I really don’t recommend everyone Blindly Purchase Bai Hao Silver Needle.

Some tea friends said that silver needles are small in quantity and scarce, and there is a high room for appreciation in the future.

Is it really?

No one knows that the future has not yet come. However, the output of silver needles is no longer low, which is an established fact.

For this year’s silver needles, tea farmers have severely affected the output of Peony King in order to pick them. It is conceivable that the price of the green tea of ​​silver needles in the next two, three, and four years will continue to rise as fast as this year. Then, in the future, the output of Peony King will continue to be affected.

Even, not only the output of Peony King, but also the output of first-class white peony will be affected.

So, at the time point of the “future” mentioned by tea friends, will the output of Baihao Silver Needle be “less”? of course not.

At that time, with the promotion of the lovely tea farmers who only love silver needles, the output of silver needles on the market must be higher than that of Peony King.

At that time, Peony King will be a scarce resource.

Even the first-class white peony will become a hot commodity because of the reduced output of the silver needles.

But now, the Baihao Silver Needle, which is estimated to be “low-yield”, will no longer be scarce because of the surge in output.

Then, can its appreciation space still occupy the high position of all white teas as people currently imagine?

Not anymore.

“4”

In addition, regarding the increase in the price of silver needles and the fact that the price of old silver needles will show a huge rate of return in the future, village girl Chen also held a wait-and-see attitude.

There are rumors that the price of silver needle tea greens soared this year, reaching the highest point in a decade, because of market misunderstandings.

According to people familiar with the matter, at the end of last year, big capital entered the white tea industry.

These capitals are newly entered. In the years before they entered, high-quality white tea, real old white tea, good tea-producing areas, and good tea mountain resources have been listed by those who entered the white tea industry in the early years.

For example, the top ten municipal-level leading enterprises in Fuding, and those in the industry who were optimistic about white tea earlier, such as the village girl Chen, carve up the white tea of ​​the early years-when they were still new white tea, of course, they have now become genuine products at a fair price. Old white tea-the early bird catches the worm.

In the Haocha Mountain in Fuding, there is a leading enterprise in each mountain that has “occupied the mountain as the king” and has included all the good tea resources in one hand.

People in the industry, such as village girl Chen, did not have the strength to wave a big hand, pointing to a certain mountain top and saying, “This mountain is contracted by me”, but they also planted a few ecological tea gardens and signed a few fixed tea greens. Supply households. (Actually, I am an authentic village girl. “The peasant woman has a little field in the spring” is my ideal)

Although the capital that has only entered now, although strong and wealthy, it has missed the opportunity-at least the root of Zhengmiaohong’s old white tea is not available for first-hand supply-second-hand supply and third-hand supply, even if it can be obtained, it may not necessarily Fidelity; even if it is fidelity, the price is not low.

Therefore, the capitals, with pride and arrogance, began to collect new white tea.

At the end of last year, the silver needles on the market in Fuding were purchased on a large scale. And, the price is surprisingly high.

This good news spread like wildfire. Tea farmers all know this “myth” about the sale of silver needles-the price of Baihao Silver Needle is rising sharply, and the big boss is buying Baihao Silver Needle!

The news soon spread all over the streets and alleys, behind the tea garden house.

Tea farmers are very excited, and silver needles are so easy to sell. So I made the ambition: next year, we will all pick more silver needles!

What the simple and simple tea farmers don’t know is, what if the capital does not come to buy Silver Needle this year? What if this year, capital suspects that the price of silver needles has risen too high and suppresses silver needles?

Isn’t it dangerous to pin the hopes of the whole family in the same basket?

How terrible is it to regard the temporary rise of a certain capital as a normal state that will continue over the years?

《5》

Jia Baoyu stared at Xie Baochai’s snow-white arm in a daze. It wasn’t that she hated Daiyu and wanted to marry her, it was just accidental hormones.

If Baochai believes that Baoyu is in love with her and is willing to conclude the Qin and Jin Dynasties with her forever, then she is really stupid.

And Second Sister You was so stupid, so stupid that she would believe Jia Lian’s words of a prodigal son, and thus took the lives of herself and the child in her belly.

Both history and novels tell us that a momentary fever does not last long.

And countless business cases also tell us that a business opportunity that happens accidentally does not necessarily become the norm.

Contrary to the practice of other industries, in the initial stage of capital entry, subsidies, price cuts, and price wars are used to win customers. When the competitor is beaten back, beaten down, and only his own family is left, the market becomes his family.

At that time, the subsidy will be gone, the price advantage will be gone, and the price will even increase in disguise-isn’t the food ordering software we use now a bloody case?

With so many lessons learned from the past, when looking at the price increase of Baihao Silver Needle, the ranking judges should be more rational.

Wait and see more, don’t be so impulsive, don’t be so easily deceived.

After three to five years, this capital has come year after year, and the state of collecting tea at a high price has been maintained year after year. That just shows that Iraq really loves white tea, is really optimistic about the white tea industry, and really wants to support white tea.

At that time, everyone will go deep into the white tea with it, buy a large amount of silver needles, and look forward to the price increase, which is the right way.

But now, obviously not in time.

《6》

The reason for buying silver needles in large quantities can be that you like to drink it; it can be that you want to save some old tea to drink for a few years; it can be that you want to give it to friends to share, but don’t just try to increase its price.

This reason is too profitable and unreliable.

You don’t always get melons when you grow melons, you may also get beans.

The laws of nature are what you think, but it doesn’t come. And you don’t think about it anymore, it might come.

Regarding the silver needle, don’t let it be too heavy.

We only need to figure out its fragrance, its mellow soup feel, and its warmth like jade.

A wave of his sleeves will not take away a cloud.

This is the most up-to-date attitude towards the top white tea like Silver Needle.

Originality is not easy, if you think this article is helpful to you, please help like it.

Pay attention to[Xiaochen Tea Matters]to learn more about white tea and rock tea!

Xiao Chen Tea Affairs Village Girl Chen, columnist, chief writer of the original innovative media “Xiao Chen Tea Affairs” in the tea industry, has published the white tea monograph “White Tea Tasting Notes”, and has written more than 4,000 original articles from 2016 to 2020.

Dr. David Muller with the high-density biopatch. Photo: Hung Vu. The technology allows researchers to use a bio-patch containing a dry layer of vaccine and then apply pressure from the injection device to deliver the vaccine into cells below the surface of the skin. Besides not using needles, this technology being tested on mice also has the outstanding advantage that it does not need to be stored in the cold chain. According to Dr David Muller, Australia’s leading virologist who was involved in the development of the new injection method, the Covid-19 vaccine delivered via a high-density biopatch induces a better immune response and faster. This technology has also shown to be more effective against dangerous variants of the current SARS-CoV-2 virus. What is unique about this single-dose vaccine technology, says Dr. Muller, is that it can help accelerate global vaccine coverage efforts, especially in low-income countries and regions of the world. remote areas. Tests to date have shown that when coated on a dry patch, the vaccine remains stable for at least 30 days in an environment of 25 degrees Celsius and 1 week if it is at 40 degrees Celsius. Using this technology, vaccines will not need to be preserved in complicated and expensive cold chains like today. The developers believe that the applicability of the new technology is very promising. In addition, scientists are also looking for funding to be able to conduct clinical trials on humans in the near future.

Busy with the job of a chief accountant at the company, but every day, Kim Thoa (38 years old, Hanoi) is still working hard in the kitchen to cook for her family. The mother of two is sharing, she loves to cook. The person who brings inspiration to the kitchen after a tiring day of work is her son. She confided, “She’s 15 years old, picky eater and very thin, so I have to regularly look up recipes online… to make him eat better.” Maybe that’s why gradually, her passion for cooking is getting bigger and bigger. It is not simply a responsibility to children, but also shows a woman’s love for her family. Kim Thoa is very passionate about cooking Currently, each meal she will cook for her family of 6, including her husband’s parents, her husband and her two sons. Every time I go to the kitchen, I will spend 1 – 1 and a half hours to cook, depending on what’s on the menu today. The cost is also carefully calculated by the mother to be appropriate and to avoid excess food, the number ranges from 150,000 to 200,000 VND/meal. Every meal I will cook for my family of 6 However, she is not too heavy on how much money is required for each meal, but for a good mother, a meal must always be nutritious and of good quality. The children are at a developing age, the elderly parents-in-law need to nourish their bodies, and the husband and wife also need health to work. Therefore, the nutrition of the meal is always her top priority. In particular, when going to the market, she always chooses fresh food. In this way, the meal will not only taste better, but also be safe and quality. The cost of her family’s daily meal ranges from 150,000 to 200,000 VND/meal. With a family of 3 generations and as large as hers, so that everyone can feel good when enjoying, Ms. Kim Thoa often arranges to cook 4 dishes in a meal. These dishes are usually soups, vegetables, stir-fries and savory dishes. She also has to regularly change the menu and the way it is prepared so that the dish is not duplicated, avoiding a feeling of boredom for everyone. “For example, today, if you eat braised pork, tomorrow you will make deep-fried fish… Especially, your own dishes will never be cooked in a week.” she says. With a daily meal, she usually cooks 4 dishes and rarely repeats the main dish in a week She also especially loves to spend weekends in the kitchen. Because this is when she has more time to change dishes, spend more time on meals. At that time, she will cook dishes such as chicken noodle soup, bun cha… for the whole family to “change the wind”. Sometimes, she also cooks hot pot, makes other dishes at the request of her children. On birthdays of family members, she dresses up to show off her talents and makes many attractive dishes. The mother confided that she especially loved the feeling of being meticulously decorated for everyone. Particularly on weekends, I will spend more time in the kitchen Perhaps, thanks to her hard work, diligence, ingenuity, sophistication and attractive cooking, everyone likes the dishes she cooks. Her father-in-law always compliments “Today’s rice is delicious” while the children say “super mom”. She admits that the dishes she cooks are really simple and not picky in terms of spices, but through everyone’s judgment, you will understand how confident she is. On weekends or on special occasions, I will meticulously decorate and cook many attractive dishes For her, family meals are very important and meaningful. “The whole family only eats together for a dinner and a weekend, so those hours are the time for the whole family to gather, talk and bond with each other. I am currently the chief accountant of a company, the I’m also quite busy, but I always take time to go to the kitchen because I feel very happy when every dish I cook, my children eat it all and compliment it.” Ms. Kim Thoa happily said. Everyone must praise Kim Thoa’s cooking skills

Our reporter/Li Mingzi Du Wei “Zhang Yu, a medical oncologist at the Third Hospital of Beijing Medical University, reflects on the shady tumor treatment by his real name” is still under investigation. Zhang Yu said in an article that Lu Wei, deputy chief physician of General Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, performed unnecessary NGS gene sequencing on patients, prescribed inappropriate chemotherapy drugs, and recommended ineffective, expensive, and illegal NK treatments (1) A series of behaviors such as cell immunotherapy), which caused the patient’s cost to increase tenfold but died earlier. Regarding several controversial issues during the diagnosis and treatment, Ma Rong, the eldest daughter of the deceased patient Ma Jincang, and the doctor Lu Wei were interviewed by China News Weekly. How to seek medical treatment for advanced gastric cancer that has metastasized? Ma Rong did not expect that the progress of medical treatment to Shanghai Xinhua Hospital would be so fast. On the afternoon of July 1, 2020, Ma Jincang, accompanied by his wife and daughter, flew from Qinghai to Shanghai. Earlier, Ma Rong only told him that there was a tumor in his stomach, and he did not explicitly say it was a “malignant tumor.” Ma Jincang’s attitude towards “seeking a doctor” was very complicated and he was instinctive to survive, but he was also worried about hearing “There is no other way.” “It’s best to go back to my hometown for chemotherapy”. On the one hand, Ma Rong encouraged his father to “visit relatives” because his sister Ma Jincang was treating stomach cancer at Xinhua Hospital. On the other hand, Ma Rong asked his aunt’s cousin to tell Ma Jincang’s condition to his aunt’s attending doctor Lu Wei, and Lu Wei listened to it. Later, he decided to let Ma Jincang come to the hospital for treatment the next day. At about 8:40 am on July 2nd, Ma Jincang walked into Xinhua Hospital. Ma Rong’s aunt (ie Ma Jincang’s sister) was discharged from the hospital on the same day. His father Ma Jincang was admitted to the hospital. He lived in the same bed as his aunt and was admitted to the Department of Orthopedic Surgery of Xinhua Hospital. The tenth floor. Ma Jincang was diagnosed with gastric cancer a month ago. Ma Jincang, who almost never went to the hospital, was notified that he was in advanced gastric cancer the first time he was “hospitalized”. The diagnosis at the Affiliated Hospital of Qinghai University showed “gastric malignant tumor”, as well as secondary liver malignant tumors and lymphatic secondary tumors. Malignant tumors, hypertriglyceridemia, hydrocele, etc. Because there is already metastatic cancer, the gastroenterologist recommends that you don’t need surgery and go directly to the oncology department for chemotherapy. Ma Rong was worried that local hospitals had limited conditions and misdiagnosis. He entrusted him to seek medical treatment in a third-class hospital in Beijing. The PET-CT examination once again confirmed the previous diagnosis. At the time of the Beijing epidemic, doctors in Beijing advised them to “go back to their hometown for chemotherapy. The cost of treatment in Beijing is high, not to mention that the beds don’t have to wait until when.” Ma Jincang heard that chemotherapy is very painful and uncomfortable, so after returning to his hometown of Haidong City, Qinghai Province, he did not go to the hospital for conventional chemotherapy. Instead, with the help and recommendation of relatives and friends, he tried some folk remedies. They even drove more than 300 kilometers and spent 40,000 yuan to buy a “small party”, “it turned out to be fooled.”

Regarding the Ma family’s motives for seeking medical treatment, Ma Rong explained, “Whoever does not yearn for birth, as far as the daughter’s affection for his father is concerned, even if the doctor says that there is a genius doctor on Snow Lotus Mountain, as a family member of the patient, I will look for it.”

At this moment, Ma Rong’s cousin found a new way. At that time, cousin Ma Rong, on the recommendation of his classmates, visited Lu Wei’s special needs clinic through an online consultation platform. After a few days of treatment for the aunt who also suffered from stomach cancer, her mental state and appetite improved.

In this way, under the recommendation of his cousin, Ma Rong took his father on the road to seek medical treatment again.

Should I do NGS sequencing and what should I do?

It takes no more than 1 hour from Ma entering the warehouse to receiving NGS gene sequencing.

At about 8:40 in the morning on July 2, after Ma Rong and his mother arrived at the hospital with his father, Lu Wei called Ma Rong and her cousin to a conference room. Ma Rong recalled that at that time Lu Wei asked her: “Is there no other hospital? Accept?” Ma Rong nodded in response. Later, Lu Wei told her: Your father’s condition is very serious and it is impossible to cure it, but according to my plan, it is no problem to live for three years. Work hard to live to five or six years.

This is the first time Ma Rong has heard from a doctor how long his father can live since his father was diagnosed. At least there is a glimmer of hope. In the conference room, Lu Wei instructed Ma Rong to “have a checkup later, people have just contacted.”

Later, a person who called himself “Manager Wu” hurried over, called Ma Rong to the safety exit of the stairs, stood in front of the window and took out the POS machine, and brushed away Ma Rong 18,600 yuan. The swiping voucher shows that the time is 9:29 on July 2nd.

Ma Rong recalled that at that time, Lu Wei called the nurse to draw blood from his father, but no one was in charge. Only one trainee nurse helped to draw two tubes of blood, which was later packed in plastic bags by “Manager Wu”. Ma Rong didn’t understand why he needed an institution other than the hospital for testing and secretly traded. His cousin told Ma Rong: “My mom did the same at the time. The results will be available a week later.”

“At the time, I couldn’t even call the name of the genetic test. After the blood was drawn, I asked Dr. Lu Wei, and he told me that it was a genetic test to find chemotherapy drugs faster. At the time, I didn’t say that a puncture should be done, nor did he say. You can take the organization for testing, I think it can be done just by drawing blood.” Ma Rong said in an interview.

However, Lu Wei explained to China News Weekly that he informed patients of the pros and cons of choosing blood and organizing tests. Lu Wei explained that when the patient came, there were multiple liver metastases from gastric cancer, multiple lymph node metastases in the abdominal cavity, and a huge metastatic lesion on the left clavicle. After taking musk for a month, it should be because the tumor was not controlled. The abdominal pain was severe and the pain was grade 6-8. , Can not eat, affect sleep. Therefore, the patient is reluctant to do another gastroscopy biopsy, and he cannot force it. The reason why NGS sequencing is done is to avoid ineffective treatment. The principle of helping patients choose a genetic testing company, Lu Wei said, is that the report can be understood by patients, the genes tested are more complete, and the results are reliable, but the price is relatively low.

However, Zhang Yu said in an article published on Zhihu that the NGS results of blood draws have almost no reference value. According to the routine, it is more accurate to detect the pathological tissue slices of the gastroscope used in the diagnosis of patients. In an interview with other media, Zhang Yu also added that the current clinical work found that NGS sequencing is extremely inaccurate in sensitivity to chemotherapy drugs and can only be used to screen targeted drugs instead of chemotherapy drugs. At the same time, the accuracy of NGS is very related to the collection of materials, especially for gastric cancer. It is very irresponsible to use blood for NGS. In the NCCN (National Comprehensive Cancer Network) gastric cancer clinical practice guidelines, this “liquid biopsy” is more used in patients whose disease has progressed and it is difficult to obtain tumor tissue samples. It is used in the CSCO (Chinese Society of Clinical Oncology) 2020 version of gastric cancer diagnosis and treatment. In the guidelines, it is listed as the third type of evidence, which is the lowest level of evidence.

The chief physician of the Department of Oncology of a third-class hospital in Beijing told China News Weekly that at present, it seems that NGS examinations are more suitable for patients with advanced stages. Of course, different tumor types have different requirements. For advanced patients, such as targeted therapy, there are mutation sites after tumor recurrence, and there are a few percent of genetic changes. Through testing, finding special drugs for the changed sites can sometimes have miraculous effects. Generally, when chemotherapeutic drugs are used in the clinic, we do not completely follow the NGS test results. NGS has relatively little reference significance, and there are more references to NGS for targeted drugs and immunotherapy.

NGS is usually detected by tissue or blood draw. “But sometimes, for example, after recurrence, the tissue is not available and it is not suitable for puncture. Then the blood is used to replace the tissue. Some tumors have been studied accordingly, and the consistency of blood and tissue in some tissues reaches 70%- 80%. When tissues cannot be taken, replacing tissues with blood NGS also has certain reference significance. I suggest that patients should be punctured. After the tissues are formed, blood will be drawn for testing at the same time, so that the accuracy rate will be higher.” The Chief Physician of the Department of Oncology of the Top 3 Hospital said.

Is there any recommendation for NK therapy?

“Whether to recommend/guide patients to adopt NK therapy” is the biggest controversy in this incident.

Lu Wei told China News Weekly that for NK therapy, “My family and I talked about the principle. They learned about it from other sources and then came to consult and decide. I didn’t take the initiative to introduce it, and they certainly did not only consult me. A person is indeed not recommended by me, and I did not stop it out of hope that my life can be effectively prolonged.”

But Ma Rong recalled, “When I heard it for the first time, I couldn’t remember the word NK. This was introduced to us by Dr. Lu Wei.” Ma Rong, who had already returned to work in his hometown on the morning of August 1, After receiving a WeChat call from Lu Wei, suggesting to give Ma Jincang “strengthen (treatment)”, Lu Wei said on the phone: “In the beginning, work hard and add a NK cell therapy. For him, recovery is better and easier. It produces results, especially when he has insufficient immunity and poor digestion of tumors.”

Before that, on the evening of July 29, Ma Rong’s mother asked her on WeChat, “I have a 30,000 yuan needle, do you want to get it?” Ma Rong felt that the cost was too high and did not agree.

However, Ma Rong insisted that the first time he heard “NK cell therapy”, it was Lu Wei who said that because he was worried that asking twice would make the doctor unhappy, so he recorded the sound and planned to listen carefully after hanging up. NK pin”. Ma Rong remembered that at the time, Lu Wei explained patiently on the phone, “Chemotherapy is a policeman, NK injection is a mercenary, and tumor is a thief. It is equivalent to the police and mercenary fighting the thief together.” Lu Wei also mentioned on the phone that his After a patient received NK injections, the lesions disappeared. “Lu Wei said that NK works well, but it is very expensive. It costs 50,000 yuan per injection. I sympathize with us from afar. It can be cheaper, but don’t say he introduced it. Yes. He said on the phone that he would send my cousin the contact information and address.” Ma Rong said.

After hanging up, Ma Rong received a document introducing NK treatment from Lu Wei, which included the name of the company “Shanghai Jiakang”. Ma Rong thought at the time, since the doctor recommended it, let his father try it. In an interview with “Medical Circle”, Lu Wei explained that before accepting Ma Jincang and his sister, he had received another pancreatic cancer patient. This patient had received NK treatment. After further treatment at Xinhua Hospital, the tumor The index dropped exponentially and was discharged smoothly. The company providing NK treatment is “Shanghai Jiakang”. The actual controller is Xu Yibing. Xu Yibing and him met at alumni gatherings. This pancreatic cancer patient had experience in the same ward with sister Ma Jincang during chemotherapy. “They learned about NK therapy during the chat, come and ask me.” Lu Wei said that he told Ma Jincang’s sister and son the principle, and told that this is not a standard treatment, and it is more expensive, it is only in the experimental stage, and may not be effective. Afterwards, Ma Jincang learned that NK treatment for patients with pancreatic cancer was free, so they asked them to help communicate and reduce the cost.

As for Lu Wei’s claim that he was once a related shareholder of a company related to “Shanghai Jiakang”, Lu Wei said that during the postdoctoral period, he and Xu Yibing’s company had CTC cooperative research. The transfer of 10,000 yuan, but this is a scientific research contract, not a share, as to why I became a shareholder, I don’t know.”

On August 3, Ma Rong’s cousin, mother and younger brother went to the “laboratory” where Dr. Lu suggested NK injections. On the same day, Ma Rong’s mother told her, “That place looks like a beauty salon.” At that time, NK injections were tested. The manager of the office also told Ma Rong’s mother that if the rich come here for injections, the wrinkles and spots on the face can be removed.

On August 10, Ma Jincang and his sister went to get the first injection of NK. With the help of Ma Rong’s cousin, the laboratory manager said that “you can buy 5 and get 1 free.” Ma Jincang and his sister each had 3 injections. Since then, Ma Jincang received the remaining two NK injections on the afternoon of August 27 and September 18.

On September 27, when Ma Jincang was undergoing a gastroscopy, a doctor sighed that “the stomach was so bad that it was so bad.” At that time, Lu Wei comforted Ma Rong as “nothing (more and more serious).” By October, Ma Jincang’s physical condition was getting worse and worse. Ma Rong couldn’t help but doubt the efficacy of the NK injection. He called Lu Wei again and asked why his aunt and father did not respond after the NK injection. “Lu Wei was angry at the time. He said that he hadn’t said that it was 100% effective. Only 70% was effective. Your dad might be the 30%. After that conversation ended unhappily, Lu Wei told my dad that your daughter didn’t Trust me.” Ma Rong recalled.

Does the surgeon plan the chemotherapy regimen?

In addition to the controversial drug selection and dosage of the second version of the chemotherapy regimen, whether surgeons can lead medical chemotherapy is also a focus of this incident.

On July 15 last year, Lu Wei told Ma Rong that because Ma Jincang was in hospital for too long, he had been complained and introduced them to a private hospital called Zhongda Cancer Hospital for the first chemotherapy. According to the information provided by Ma Rong, the chemotherapy drug at that time was oxalibo + fluorouracil.

According to Ma Rong’s recollection, after the “unpleasant call” in October last year, Lu Wei’s attitude became cold and he changed his father’s chemotherapy regimen at the same time. Starting from the fifth chemotherapy, the patient’s chemotherapy regimen changed to a combination of pemetrexed, anlotinib, oxaliplatin, capecitabine and tamoxifen. At the same time, Ma Jincang on October 3 ” “Intravenous chemotherapy drugs” still write “Lu Wei” in the column of the operating physician.

Regarding the reasons for the replacement of chemotherapy drugs, Lu Wei said: After adopting the first-line treatment plan, the patient’s first 2 cycles of treatment are effective in symptom control, and “you can eat and sleep.” But the blood AFP continues to rise to more than 10,000, and it may be more than 7,000 when it comes. Therefore, during the 2-3 cycle, it is recommended to evaluate with the family members, “The evaluation shows that the liver lesions are in a stable state, and the supraclavicular lymph nodes have disappeared. However, the patient’s symptoms reappear.” After discussing with the patient, the family members said that the patient was young and decided to adopt Individualized treatment plan. Moreover, the patient’s NGS results showed low sensitivity to paclitaxel and high side effects of irinotecan, and then recommended the above-mentioned second-line drugs, referring to the Chinese and English literature and drug principles of this disease. After this, Lu Wei was sent to Hainan without further follow-up treatment. “In fact, the family members only partially implemented this plan. They should have multiple consultations, but the follow-up did not go on.” Lu Wei said.

But Ma Rong did not agree with this statement. “My father took the chemotherapy drugs for a long time, and I bought anlotinib from outside after taking it. Up to now, there are only one or two of each drug left.” Ma Rong said.

It is worth pointing out that Lu Wei is not an oncologist, but a general surgeon. A medical oncologist at a top domestic oncology hospital said that such authorization is not allowed abroad, but in China, it is not uncommon for surgeons to perform medical treatments and perform tumor chemotherapy in surgery. Another doctor told China News Weekly that surgeons cannot lead internal medicine treatment plans. As doctors who traditionally dominate tumor treatment, it is understandable that surgeons habitually write some plans for reference. The final internal medicine plan should be decided by multidisciplinary consultation. .

In Ma Rong’s impression, his father’s chemotherapy regimen does not seem to have undergone “multidisciplinary discussion.” Ma Rong recalled that every time she went to Lu Wei’s office to consult her father’s condition, Lu Wei would ask her to wait until after get off work, or after other doctors had left, or she would go into the corridor and say, “I feel he is evasive. The doctor asked him those questions.” Ma Rong said.

Is it a good doctor or a bad doctor?

At the end of October last year, Ma Jincang, who had undergone NK injections and the second version of the chemotherapy regimen, was already thin to the point. At the time, Ma Jincang always said that the back spine hurts. Ma Rong didn’t know that it was cancer pain, or even that his father had bone metastases. Before that, every time he asked Lu Wei about the progress of his father’s condition, Lu Wei said, “Yes. very good”.

Unwilling to reconcile, Ma Rong asked for leave to accompany his father in Shanghai, and on November 1 he went to the clinic of a doctor surnamed Zheng in the Oncology Department of Xinhua Hospital. At that time, the other party had read all the treatment records and told Ma Rong that he and Dr. Lu were in the same hospital. It is hard to say much, but “this treatment is ridiculous.”

After that, Ma Jincang underwent another chemotherapy. Ma Rong had already returned to the Qinghai class. His mother was illiterate, and every time he accompanied his father to see a doctor, he had to ask people around. Ma Rong couldn’t bear the tossing of the old couple, and he also followed the doctor’s advice to “take the old man back to his hometown while he was alive.” On December 24, 2020, Ma Jincang passed away in the arms of his wife at home. In March of this year, sister Ma Jincang passed away.

After the death of the two elderly people, on April 9, 2021, Ma Jincang’s eldest son also wrote a thank-you letter to Lu Wei. The letter stated that during the entire treatment process, “Dr. Lu Wei was very concerned about the treatment of the two elders”, “After the treatment, my uncle’s stomach seldom hurts and the bulge on his neck disappeared.” But Dr. Lu Wei thinks He is in a special condition and the laboratory test results are not satisfactory.” So he adopted a special medication plan, and informed him about the dosage, side effects, and time of taking the medication. The letter also stated, “During the treatment, Dr. Lu Wei never tricked us into spending high prices on treatment, but instead helped us save money everywhere.”

But on the same day, Ma Rong reposted Zhang Yu’s latest article on his Weibo and wrote: “If this will worsen the doctor-patient relationship, then the people really deserve to be deceived, and the world is the power of the strong. The doctors in the big hospital expected that we were from the countryside, and there was no way to get him, so we asked us to get a 30,000 injection of cell needles, giving us hope at a time, letting us down again and again, until Dad was gone. If this is the case, go to death if you get sick in the future, because when you go to the hospital, you will also die.” On April 2 before this, Zhang Yu published an article criticizing Lu Wei for the first time. Regarding the thank-you letter, Ma Rong said, “I don’t know, I didn’t write it.”

“Is NK treatment legal? Will the NK injection be as effective as Dr. Lu Wei said? If it is illegal and ineffective, why do doctors in large hospitals say such things to patients? We only ran from Qinghai to Shanghai for treatment. I only hope that this matter can be investigated clearly. Don’t wrong a good doctor or let go of a bad doctor.” Ma Rong said in an interview that this is her. The final appeal.

Recently, netizens stirred a story about a 5-year-old girl whose parents gave her cosmetic collagen tattoo spray.

Accordingly, the owner of a Facebook account shared: “The 5-year-old child, if you look and get motivated, look at me whoever is afraid of pain”.

The post made netizens angry because spraying tattoos is a beauty method that should only be used for adults. According to information from social networks, the incident happened from March 2021.

On February 21, 2021, the person who directly sprayed her with tattoos was her biological father – who is running a salon business.

The girl’s father explained about the baby’s lip tattoo: “Nowadays, most of the students who go to school like to use lipstick that is prone to lead, which is very harmful in the future, so ST has made lips for girls to be safer for girls. “.

The parents of the 5-year-old baby, known as the owner of the salon, shared a status: “The 5-year-old child, if you look at it, get the motivation, the girl who is afraid of pain, look at me”.

Assessing the issue of lip tattoo for 5-year-old children is causing a stir recently, Dr. Tran Ngoc Anh – Ho Chi Minh City Dermatology Hospital informed by Dan Viet newspaper that it is really difficult to accept lip tattooing. for 5-year-olds just to have pink lips.

The act of lip tattooing for a 5-year-old baby has a lot of potential risks affecting the health of the baby because at that age, children are having many changes.

According to Dr. Anh, for medical aesthetics, there is no age limit because there are cases where the baby has a birthmark or has a problem that requires intervention and must be appointed by a specialist. And the act of bringing such a baby out for cosmetic purposes is not good.

Lip tattooing is a method to help improve dark lips, pale lips, make lips more rosy, sexy, shorten makeup time, but this is a method that contains many risks and possible complications. happening.

According to doctors, compared with tattooing in other areas of the body (eyebrow tattooing, eyelid tattooing …), the complication rate of lip tattooing is more common. For tattooing each month at the hospital receiving examination and treatment for about 1-2 complications.

In particular, not only the complication rate is higher, many cases of lip tattooing have serious complications that are difficult to treat such as: infection at the tattoo site, causing swelling, redness, bleeding, pimples, self-pus. , inflammation increases pigmentation causing darker lips or damaged tattoos causing deviation, bad scars permanently on the lips …

There have been many cases of complications after lip tattooing. Illustration.

Lip tattoo, lip spray are two methods of bringing tattoo ink into the skin or mucous layer, depending on the depth that can be called different tattooing or spraying.

Lip spray is a technique using a tattoo sprayer with a micro-needle tip, inside with an ink bulb that impacts the lips with a depth of no more than 0.2 mm, bringing tattoo ink into the epidermis of the skin, time Less resting, less swollen lips, but poor color fastness.

Lip tattoo is the technique of using a needle to pierce the horny layer, then apply tattoo ink evenly or dip the needle in the ink first and then apply it to the skin to bring the tattoo ink into the deep layer of the skin, possibly through the bottom layer to the dermis.

With the depth of action on the lips, the lip tattoo technique helps to make the color more durable, but there is a potential risk of complications, often causing damage to the mucous layer so tattooing can cause bleeding. After the tattoo, the lips are swollen and large, possibly causing infection.

In cases of tattoo ink of unknown origin, the implementation process is not sterile, the performers are not sure about the expertise, both lip spray and lip tattoo are potentially dangerous.

MSc. Tran Nguyen Anh Tu – Deputy Head of Department of Aesthetic Skin, Ho Chi Minh City Da Lieu Hospital emphasized in the health and life newspaper that lip tattooing hides a lot of risk of complications. Firstly, there is the risk of infections, viral infections such as hepatitis B, C, HIV… if the operator does not ensure the environment and sterile techniques.

Next is the use of poor quality tattoo ink, cheap can cause severe allergic reactions at the tattoo site such as swelling, red skin, blisters …

In the case of using a good tattoo ink, it is impossible to completely rule out an allergic reaction to tattoo ink, especially red tattoo color. Finally, the care after performing the tattooing technique is also very important, in most cases there are complications because the place where the tattooing technique does not advise or advise on the wrong way of taking care of the tattoo.

MSc.BS Tran Nguyen Anh Tu – Deputy Head of Department of Aesthetic Skin, Ho Chi Minh City Da Lieu Hospital recommends, in fact, women’s beauty needs are justified, for safe beauty, women Priority should be given to choosing a solution to use lipstick.

Using lipstick is also more fashionable because it can change quickly with trends.

In the event that women still want to choose the lip tattoo method, they should carefully research, choose reputable facilities, ensure sterile equipment and procedures. If a lip tattoo accident occurs, it is advisable to go to the hospital as soon as possible, to avoid mistreating it, causing the injury as badly as possible, and recovering more difficult.