All of these vaccines are allocated to priority subjects according to Resolution 21 and localities with industrial parks. Vaccines for COVID-19. Photo: Times of India. In addition, from now until the end of the third quarter, Vietnam will also receive an additional 2 million doses of AstraZeneca’s vaccine ordered by the Ministry of Health through VNVC. In the third quarter, information from the pharmaceutical company Pfizer said that 3 million doses of vaccine can be shipped to Vietnam, the rest will be concentrated in the fourth quarter. However, the specific time and quantity may change due to dependents. of the world situation. According to Professor Dang Duc Anh, the COVID-19 vaccine has a very short shelf life, only about 6 months. Meanwhile, the time from the production facility to Vietnam takes about 2 months, so it only takes 3-4 months to deploy the injection. In particular, Pfizer’s vaccines must be stored at deep minus temperatures (-70 degrees Celsius). If the temperature is 2-8 degrees Celsius, this vaccine is only used for one month. Therefore, in the coming time, the Ministry of Health will coordinate with units of the Ministry of National Defense across the country to ensure the preservation and transportation of vaccines to the injection point in the shortest time. Up to this point, Vietnam has urgently approved four COVID-19 vaccines: AstraZeneca, Sputnik V, Sinopharm and Pfizer. Vietnam aims to have 150 million doses of COVID-19 vaccine this year for at least 70-80% of the population, to form herd immunity. However, only 4 batches of AstraZeneca’s vaccine have arrived in Vietnam with a total of nearly 2.9 million doses. Earlier, Minister of Health Nguyen Thanh Long stated that Vietnam is facing the 4th wave of COVID-19 epidemic with the Delta variant of SARS-CoV-2 capable of spreading quickly and widely. The Vietnamese government is drastically directing epidemic prevention and control measures to soon stabilize the situation. One of Vietnam’s priorities in COVID-19 prevention is to have a COVID-19 vaccine early and to implement broader vaccination coverage for the population. Therefore, in parallel with efforts to find, negotiate and discuss with partners and vaccine manufacturers to bring vaccines to Vietnam, the Ministry of Health and related ministries and branches also focus on developing domestic vaccines to gradually ensure vaccine autonomy. At the same time, Vietnam also participates in COVAX’s global vaccine supply mechanism.

“I have a strategy and I will publish it.” Biden said when asked about the vaccine strategy for the world before boarding Air Force One to fly to the UK for the G-7 summit. The US will donate 500 million doses of the Pfizer vaccine to the world. (Photo: CNN) Sheet The Times said Mr Biden would appear alongside Pfizer CEO Albert Bourla to make the announcement. According to the AP , of these 500 million doses, 200 million doses will be shared this year. The rest will be donated in early 2022. Washington Post was the first newspaper to publish this information. Many newspapers later cited sources confirming the above information. The US is facing increasing pressure to draw up a plan to share vaccines with the world as its vaccine campaign is inching towards the finish line. Last week, the White House announced plans to allocate the first 25 million doses of the vaccine, with 19 million going to COVAX and 6 million to current COVID-19 hotspots including India. These vaccines are among the 80 million doses of vaccines the US has pledged to share with the world this month.

Pfizer’s Covid-19 vaccine vial. Photo: Reuters. The European Commission, on May 28, approved the use of the Covid-19 vaccine from Pfizer and its partner BioNTech for children 12 years of age and older, paving the way for the implementation of vaccinations for children of all ages. widely within the bloc, after similar decisions were made by the US and Canada. The decision came after the European Medicines Agency (EMA) advocated the use of the vaccine in children aged 12 to 15 years earlier. This vaccine has been used in the European Union for people 16 years of age and older. For the 12-15 age group, the two doses of the vaccine are also given at least three weeks apart, as with adults, the EMA said. According to the EMA, each EU country will decide whether and when to provide the vaccine to adolescents. While awaiting the decision of the EMA, on May 27, Germany outlined a plan to provide vaccines for children from 12 years old from June 7. Italy also said that it is preparing to expand its Covid-19 vaccination campaign to people over 12 years old. Immunizing children and adolescents is seen as an important step towards achieving “herd immunity” and taming the pandemic. On May 28, Japan also joined other countries that decided to give the Pfizer vaccine to children as young as 12 years old. Since March, Pfizer and Biontech have released trial data showing that their Covid-19 vaccine is 100% effective in protecting against infectious disease in a trial of 2,260 adolescents aged 12 to 15 years. .

Clinical trials of the Pfizer vaccine showed up to 95-96% effectiveness against invading coronaviruses. According to the New York Times , each batch of Pfizer-BioNTech vaccine with 7.5 million doses is produced in 60 days. The most advanced mRNA technology The Pfizer-BioNTech vaccine uses mRNA technology. This vaccine is recommended by the US Centers for Disease Control and Prevention (CDC) for use in people 12 years of age and older. The SARS-CoV-2 virus carries proteins that allow it to enter human body cells. These proteins – known as spike proteins – are the subject of research in the production of vaccines and drugs to treat Covid-19. Coronavirus. Photo: New York Times. Pfizer-BioNTech’s vaccine is based on the genetic makeup of the SARS-CoV-2 virus to create artificial protein spikes. Vaccines use messenger RNA (mRNA), a type of genetic material that human cells process to make proteins. The messenger RNA molecules are very fragile, so they will be broken down by natural enzymes in the human body if injected directly into the human body. To protect the mRNA in the vaccine, Pfizer-BioNTech wraps the mRNA molecules in an oil bubble made of microscopic fat particles. mRNA molecule. Photo: New York Times. Due to their unstable nature, the mRNA molecules in the vaccine will be degraded at normal temperatures. Therefore, vaccines of Pfizer-BioNTech need to be stored at deep cold temperatures, at least -70 degrees Celsius or less. To keep the vaccine of Pfizer-BioNTech stable, special containers are required, including dry ice, heat sensors and GPS trackers. Inject vaccines into the body After vaccination, the molecular particles in the vaccine will collide and fuse with human body cells, releasing mRNA. Human body cells will read the genetic content contained in the mRNA and from there produce protein spikes. The mRNA molecule from the vaccine is eventually destroyed by human cells forever. Vaccine molecules interact with cells. Photo: New York Times. Some protein spikes will form spikes, which rise to the surface of the cell and protrude outward. Cells that have been affected by the vaccine also break down the protein into small pieces on the surface. The protein spikes protruding from the cell, and the protein molecule on the cell surface, will eventually wake up the human immune system. When cells that have interacted with the vaccine die, their fragments contain many protein spikes and protein fragments. These fragments will be picked up by a type of immune cell called molecular antigen-presenting cells (APCs). APC cells activate helper-T cells. Photo: New York Times. Fragments of protein spikes will stick to the surface of APC cells, until helper-T cells detect these fragments. The helper-T cells then trigger the immune system to produce antibodies against the coronavirus. Antibody production Other immune cells, called B cells, can collide with the coronavirus spike protein on the surface of the cell that has interacted with the vaccine, or the floating protein spike debris. Some B cells can adhere to protein spikes. Helper-T cells activate B cells that help produce antibodies. Photo: New York Times. When B cells are activated by helper-T cells, they begin to produce antibodies that attack the spike protein. Antibodies neutralize corona virus. Photo: New York Times. The antibody produced will attach to the spike protein of the invading corona virus. Antibodies mark the virus for later destruction by the body’s immune system. More importantly, the antibody prevents the viral spike protein from attaching to the healthy cells of the human body. To destroy the virus, APC cells activate another type of immune cell called cytotoxic-T cells. This cell is responsible for finding and destroying cells that have been infected by the virus through the signal of protein spike fragments on the surface. Cytotoxic-T cells destroy infected cells. Photo: New York Times. Remember information about corona virus Pfizer-BioNTech’s vaccine is given in two doses, 21 days apart, to help the immune system work most effectively against the corona virus. But because of the lack of time to study, scientists cannot be sure how long the immunity created by the vaccine will last. Preliminary research shows that within 10 days of receiving the first dose, the vaccine begins to build a strong immune system against the virus. It is likely that, after several months of vaccination, the number of antibodies and cytotoxic-T cells will gradually decrease. But the immune system also contains special cells that store information about the corona virus for years, even decades. Each vial of vaccine contains 5 injection doses of 0.3 ml. Vaccines need to be thawed and diluted with saline. After dilution, the vaccine must be used within 6 hours.