On April 24, talking to PV Tien Phong, Binh Duong’s police representative said that in order to keep up with the set schedule, the unit was strengthened to implement the work of granting CCCD to local people. On the upcoming 4-day holiday, the police of Binh Duong province still work day and night and do not take a rest. Binh Duong police issued CCCD to people during 4 holidays With the goal of completing the issuance of CCCD cards to all people aged full 14 years and over in the area by July 1, 2021, Binh Duong Provincial Police has focused on maximum all available resources, including “Overtime” works at night to keep pace. Colonel Trinh Ngoc Quyen, Secretary of the Party Committee, Director of Binh Duong Provincial Public Security said that the whole province is currently equipped with 20 apparatuses by the Ministry of Public Security to issue CCCD cards to people. In order to meet the needs of people to use CCCD cards and ensure the right time as prescribed by the Ministry of Public Security, Binh Duong Police gather all available resources to issue CCCD cards 3 shifts / day, day and night continuously. including working on Saturdays and Sundays and increasing mobile work in communes, wards and towns. Binh Duong is located in 10 provinces and cities selected by the Ministry of Public Security as the implementation point to be completed until July 1. Ethnic minorities in Binh Phuoc are offered free transportation to CCCD In Binh Phuoc province, the police force was arranged to increase working day and night to timely issue CCCD to the people. The current time in Binh Phuoc is the cashew season, during the day people are busy harvesting cashew, often take advantage of at night to get citizenship. This is a locality where there are many ethnic minorities living, the way at night is very difficult. People in Binh Phuoc harvest cashew during the day, and work as CCCD at night In order to support ethnic minorities, where traveling is difficult, the police of Phu Rieng commune (Phu Rieng district) mobilized a 52-seat passenger car to carry and pick up people for free from 7:00 pm the previous night. 5 o’clock the next morning. Only on April 23 and 24, about 300 people were brought in, including priority for the elderly, students, pregnant women, young children, families with no means of transportation …

Economic development model in net-house in Nghia Thuan commune (Thai Hoa town). Photo: Nguyen Nguyen Through reality, the members of the cooperative work with the hamlet’s cell, promoting more positive effects. Mr. Tran Huu Son – hamlet 5, Nghia Thuan commune (Thai Hoa town) Like Party member Tran Huu Son, 6 other members in the management apparatus of Nghia Thuan Agricultural Cooperative also registered to live in 5 Party branches in the locality. Every year, comments of the branches and members of the cooperative are assessed to have successfully completed their tasks, and have close ties with the local people. Through an exchange, Mr. Tran Huu Son said: “In principle, a cooperative can establish a Party cell. But in reality, the members of the cooperative work with the hamlet’s cell, promoting more positive effects. Through the Party’s activities at residence, we can grasp more information and aspirations of the people and members in economic development, then put into the daily discussion content of the management board. cooperative. On the contrary, through the activities, they also promptly coordinated with the cell in propagating the directions and development plans of the cooperative so that the party members and the people could participate. Such a “shuttle” has a practical effect “. Nghia Thuan commune Party Committee (Thai Hoa town) has 15 branches with 467 members. Currently, schools and commune people’s credit funds maintain independent branches, and all party members are civil servants, part-time workers in the commune are assigned to live in 7 village and hamlet branches. Over the years, party members who are civil servants, part-time activists of the commune actively and at all levels have actively contributed to building a clean and strong political system, improving leadership capacity and strength. fighting of the party organization. Along with that, strengthening the block of great unity, promoting economic development, ensuring national defense, security, social order and safety. Mr. Tran Huu Son – Director of Nghia Thuan Agricultural Cooperative (Thai Hoa Town) introduced the model of growing shiitake mushrooms. Photo: Nguyen Nguyen Comrade Bui Van Chinh – Permanent Deputy Secretary of the Party Committee of Nghia Thuan commune said that all party members who are civil servants and part-time activists of the commune have brought into play their roles and responsibilities, together with other branches. effectively implemented Party directives and resolutions at all levels, step by step improving the people’s material and spiritual life. In Vinh city, the dissolution of 25 branches in ward and commune offices is done later than districts and towns (from June 2019). Currently, there are over 520 Party members who are cadres and civil servants in wards and communes of the city living in blocks and hamlets. According to the Vinh City Party Committee’s Organizing Committee, depending on the fact, each ward and commune has appropriate ways to assign the number of party members to blocks and hamlets to promote efficiency, contributing to positive changes at the grassroots level. . Party member Nguyen Thanh Hai – Deputy Team of the Urban Order Management Team of Nghi Phu commune (Vinh city) is now taking on the title of Secretary of the Sub-ward of Hamlet 5 of the commune. The difference is that this is not the residence of Mr. Hai (his house is in hamlet 17, Nghi Phu commune). Due to the requirements of the mission, Mr. Hai and 6 other party members working in the commune were assigned to work in the Party cell in Hamlet 5, in the area where more than 85% were parishioners. Party activities and the secretary of the Party cell in other areas where he resides, so besides fulfilling his professional tasks well, Mr. Hai has to invest more time with the staff, organizations and unions. Village 5 captures the reality, discussing solutions to perform assigned tasks. Party member Nguyen Thanh Hai – Deputy Team of the Urban Order Management Team of Nghi Phu Commune, Secretary of the Sub-ward of Hamlet 5 and the Leader of the village visit difficult families in the area. Photo: Nguyen Son The important thing is that each party member in the cell is really attached to the organizations and unions, increasing meeting and talking with the people, thereby supplementing the action plan closely with reality. Performing such “dual” duties, Mr. Hai’s responsibilities are heavier than those of other cadres and civil servants. But he has arranged a suitable time, besides completing professional tasks, Mr. Hai and the “strengthening” party members have cooperated closely with the cadres and organizations and mass organizations in the neighborhood to meet remove, exchange with people, organize the implementation of many emulation movements, actively in social security work. Mr. Hai said that, with the assigned tasks, he and his colleagues and comrades tried their best to achieve the highest efficiency. The important thing is that each party member in the cell is really attached to the organizations and unions, increasing meeting and talking with the people, thereby supplementing the action plan closely with reality. Conclusion No. 134 – KL / TU of the Standing Committee of the Provincial Party Committee dated March 5, 2019, on solutions to rearranging organizational structure and restructuring the contingent of cadres and civil servants of the communal political system of Nghe province Lean, effective and efficient operation is being carried out synchronously in all localities. With regard to the re-arrangement of the contingent of officials, civil servants and part-time activists at the commune level, the Standing Committee of the Provincial Party Committee states: For other titles that are entitled to allowances according to the resolutions of the provincial People’s Council, they are not. Separately arranged that must be associated with at least 1-2 other titles, such as: Commune-level civil servant part-time, or attached to positions in the block, hamlet, village or village (secretary, village chief, chief festival…). This content has been applied by many localities, appointing party members who are cadres and civil servants to assume the title of Party Cells’ secretaries, contributing positively to improve the quality of activities of local branches. This is one of the solutions to implement the motto of building a strong political, ideological and organizational Party, focusing on improving the leadership capacity and fighting strength of Party organizations and party members. The whole province of Nghe An currently has 193,515 party members; Of which, more than 15,000 party members are cadres, civil servants, part-time workers in communes, wards, towns and workers in cooperatives, enterprises in districts and communes living at 5,630 branches. Block sets, hamlets, villages. A corner of Vinh city. Documentary photo: Lam Tung

Xinzhiyuan Report

source:Academic headlines

【Xin Zhiyuan Guide】A new generation of Xenobots-They are assembled into the body automatically through single cells, and after assembly they can be moved without the aid of muscle cells, and even demonstrated the ability to store memories.

Last year, a team of biologists and computer scientists used frog cells to create a new type of miniature self-repairing biological robots called “Xenobots”-biological machines that can move around, push heavy objects, and even make Group behavior.

Today, the team has successfully developed a new generation of Xenobots on this basis-they are automatically assembled into a body through single cells, and can be moved without the aid of muscle cells after assembly, and even demonstrated the ability to store memories. The new generation of Xenobots robots move faster, can move in different environments, and have a longer service life. At the same time, they still have the ability to teamwork and can repair themselves after being damaged.

Researchers say that this versatility makes it possible for Xenobots robots to perform tasks in more environments. Relevant research results were titled “A cellular platform for the development of synthetic living machines” and were published in Science Robotics magazine on March 31.

(Source: Science Robotics)

Shuttle at will, just because of this special “leg”

It is understood that the researchers used artificially “modified” heart cells in the previous generation of Xenobots robots. Due to the natural rhythmic contraction of these cells, Xenobots robots have the ability to move around.

In contrast, the new generation of Xenobots robots adopts a “bottom-up” approach. The extracted frog stem cells self-assemble and grow into spheroids. The cells in some spheroids will differentiate to produce cilia-like tiny hairs after a few days. Protrusions, these protrusions can move back and forth or rotate in a specific way.

The corresponding author of the paper, director of Allen Discovery at Tufts University, and professor of biology, Michael Levin, said: “We are witnessing the plasticity of cell clusters. Although these frogs have completely normal genomes, we use their cells to construct A new’body’ completely different from the default state.”

At the same time, these cells can also reuse their genetic coding hardware to achieve new functions, such as using cilia to achieve movement. Even more surprising is that they can not only take on new roles spontaneously, but also create new physical behaviors without the need for long-term evolutionary selection of these characteristics. ”

Figure | Xenobots move through cilia and show teamwork ability

In order to test the ability of a single Xenobots to move in different environments, the researchers constructed different experimental environments from a completely open field to a restricted capillary with an inner diameter of 580nm. In all cases, except for some Xenobots that were challenged in narrow passages, Xenobots were able to move in space.

Under certain circumstances, Xenobots may move in the opposite direction. The reason is that the intracellular and tissue-wide polarity is established by cell rearrangement during the self-assembly stage created by Xenobots, and cannot be changed on a short time scale. Therefore, the rapid changes observed in the study may be due to real-time control of cilia, such as changes in the beating frequency of individual polyciliated cells, rather than changes in structural polarity.

Like many unicellular and multicellular organisms that use cilia for exercise, this exploratory behavior (spontaneous changes in exercise) may be affected by random internal physiological processes and micro-changes in the environment, such as spontaneous currents in an aqueous medium.

In the experiment, when the channel width of the “maze” is reduced to 2mm, Xenobots will continuously hover around a wall of the maze. According to observations, most Xenobots tend to exhibit an elliptical movement pattern. This behavior may be due to the wall inhibiting the completion of the elliptical path, which in turn drives the final directional movement.

Figure | Xenobots can pass through a variety of terrains including mazes

In addition, the researchers placed Xenobots on one end of a 2cm capillary with an inner diameter of 580nm. Unexpectedly, 42% of the tested Xenobots were able to pass through capillaries end to end. All individuals exhibiting movement successfully passed through the entire capillaries, and none of them stayed or reversed in the middle between the two ends. To movement.

Figure | Xenobots through tiny capillaries

The researchers said that these data are sufficient to show that Xenobots can successfully traverse various environments without having to go through a special configuration to adapt to a given scene, which is an ideal feature in many software robot applications.

Stronger collection and handling functions

At the same time, the researchers also modeled Xenobots of different shapes to determine whether they exhibit different behaviors when they are alone or in a “team”.

They hope that Xenobots can do some meaningful work in real life, such as life tools for removing microplastics in the ocean or pollutants in the soil. Facts have proved that the new generation of Xenobots is faster and better than the previous generation model in tasks such as garbage collection. They can clean the petri dishes in groups to collect larger iron oxide particles.

Figure | Xenobots work together to collect piles of tiny particles

In addition, Xenobots can also cover larger flat surfaces or move in narrow capillaries. These studies also show that in the future, computer simulation can optimize the additional functions of biological robots to adapt to more complex behaviors.

Also has a memory function? !

The core feature of robotics is that it can record information and use this information to modify the actions and behaviors of the robot. In order to confirm whether Xenobots have this function, the researchers designed a Xenobots with read and write functions, and they used EosFP’s fluorescent reporter protein to record this information. This protein usually emits green light, but when exposed to 390nm wavelength light, this protein can emit red light.

Researchers injected messenger RNA encoding the EosFP protein into the cells of frog embryos. Xenobots made from these stem cells have a built-in fluorescent switch that can record blue light exposure around 390nm.

To test the memory function of Xenobots, the researchers let 10 Xenobots move on a surface where a spot is illuminated by a 390nm beam. Two hours later, they discovered that three robots were emitting red lights, while the rest remained green, effectively recording the robot’s “travel experience.”

Figure | Xenobots can record information by changing the color

In the future, this proof of the principle of molecular memory can be extended to detect and record light, radioactive contamination, chemical pollutants, drugs, and diseases. The further design of the memory function can record multiple stimuli, allowing the robot to release compounds during the stimulus, or to change its behavior based on the sensation of the stimulus.

Bongard said: “When we give robots more functions, we can use computer simulations to design more complex behaviors and the ability to perform more complex tasks. We can not only report the conditions in their environment, but also modify and Repair the conditions in its environment.”

Even self-healing

What’s more surprising is that the new generation of Xenobots is also very good at “healing” their wounds, and can heal serious full length lacerations by half the thickness within 5 minutes of injury. In the experiment, all the injured robots eventually healed their wounds, restored their original shape, and continued to work as before.

Figure | Xenobots can repair itself

The researchers said that one of the advantages of biorobots is metabolism. Unlike metal and plastic robots, the cells in biorobots can absorb and break down chemicals and work like small factories such as synthesizing and expelling proteins. The entire field of synthetic biology previously focused on reprogramming single-celled organisms to produce useful molecules, and now it can be used in these multi-celled organisms.

Like the previous generation, the upgraded Xenobot robot can survive in the embryonic energy store for up to 10 days and run tasks without additional energy. However, if they are kept in a nutritious “soup”, they can also run at full speed for several months.

Before, Levin introduced a wonderful description of biological robots in a TED talk, and he also described what we can learn from these biological robots. He not only described the great potential of micro-biological robots to perform effective tasks in the environment or potential therapeutic applications, but also pointed out the most valuable benefits of this research, using robots to understand how individual cells gather, communicate, and specialize to create greater The organism. This is a new model system that can provide a basis for regenerative medicine.

The researchers said that Xenobots and subsequent alternative versions are also expected to provide information on how ancient single-celled organisms evolved into multicellular organisms, as well as the origin of information processing, decision-making, and cognition in biological organisms.

Reference materials:

https://now.tufts.edu/news-releases/scientists-create-next-generation-living-robots

http://dx.doi.org/10.1126/scirobotics.abf1571