Home Science Dr. Tran Bac Hai: The principle of ‘infection or death’ of SARS-CoV-2...

Dr. Tran Bac Hai: The principle of ‘infection or death’ of SARS-CoV-2 and our way out

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Co Vi’s principle of existence (and many other infectious viruses) is ‘infect or die’. Viruses are not cells, so they cannot reproduce outside of the body, and when outside the body, Co Vi does not last long.

How to get rid of Miss Vi? To get out of pandemics like Co Vi, it is now clear that it is not possible to rely solely on social distancing measures and aggressively tracing the virus. Closures and tracing are very important measures, and the Vietnamese government has excelled in the early stages of fighting the epidemic with these measures alone. But in an open world, the border door can’t close no matter how hard it is, tracking the ghost of Co Vi successfully this time but still wondering when it will come back. But if you keep busy with “national resistance”, “defensive counterattack”, you will be hungry all the time. Relying on medical treatment is even worse, because firstly, there is no medicine to guarantee that 100% of people infected with Co Vi will survive; the second (and more important) is that when there is an outbreak, the health system simply collapses, you have very little chance of being hospitalized, and if you do get into the hospital, there will be no more oxygen to breathe. . Some of my friends whispered to each other (=Phew) measures to eradicate Co Vi such as drinking hot water, eating garlic, steaming with leaves, or simply… fiercely drinking! If you apply it to yourself, it won’t hurt anyone other than your spouse, children, or grandchildren, but I beg you not to incite Phai to do the same, because that is verbal karma. Miss Vi is “contagious or dead” and our way out Co Vi’s principle of existence (and many other infectious viruses) is “infect or die”. Viruses are not cells, so they cannot reproduce outside of the body, and when outside the body, Co Vi does not last long. When the majority of the population is immune, the probability of transmitting Co Vi decreases, even those who are not immune are protected, the epidemic will be basically extinguished. This is the phenomenon of “herd immunity”, which has long been observed and concluded by scientists with many previous pandemics. Herd immunity can occur during natural epidemics. After about 70% of the population has been infected with Co Vi, about 1-5% will die, the rest will become immune. Assuming Vietnam followed this model, it would have to sacrifice about a million people. Certainly most of us disagree with this measure. There is another way that does not require such sacrifices to achieve herd immunity, which is to vaccinate the majority of the population. Immune cells can be “trained” to recognize Co Vi by the S protein molecule on its surface. When real Co Vi invades, immune cells secrete antibodies that “lock hands” with these S proteins. Co Vi’s protein S mimics the body’s ACE (angiotensin-converting enzyme) molecular structure to adhere to cell surfaces. If protein S is surrounded by antibodies, then Co Vi also “botay.com”. Not everyone wants a vaccine But in the world there is a part of people who think they will not get vaccinated. Some even think that this is a conspiracy of certain forces to invest a lot of money to profit on the sacrifice of their fellow human beings. Others will not go for injections because they find it annoying, or afraid of spending money. Attitude to vaccination is a personal choice, but is greatly influenced by social relations, by the community to which the individual belongs. Here, I would like to introduce two social issues that have a great influence on the attitude to accept vaccination, which have been analyzed quite meticulously by sociologists. 1. Religion and vaccines (Main reference: Pelcic et al 2016. Religious exception for vaccination or religious excuses for avoiding vaccination Croat Med J 56(5):516-521) Religious beliefs have a huge influence on vaccination acceptance attitudes. All major religions have favorable attitudes towards vaccination. The first precept of Buddhism is abstaining from killing, so Buddhists accept vaccinations to keep themselves and others healthy. On the other hand, Buddhism considers all species to be non-killing beings, and believes that humans can also be reincarnated into other beings. Thus killing animals for vaccine research may be contrary to Buddha’s teachings. The Catholic Church does not prohibit vaccination. Historically, Catholic and Anglican missionaries (Catholics in England and some former British colonies) have inoculated with smallpox in North America. Today’s development of biomedical research leads to an issue that may contradict Catholic doctrine, which is that some vaccines are produced on cultured cell lines of fetal origin, specifically Meruvax. , Rudivax and MR-VAX (Rubella prophylaxis), A-VAQTA and HAVRIX (hepatitis A), Varivax (chickenpox), and Polivax (smallpox). But when there are no other vaccines to choose from, parishioners are still encouraged to vaccinate to protect young children and the community, especially pregnant women. In Islam, food is divided into two categories, halal is allowed, and haram is not. Pork is haram, so pharmaceuticals that use gelatin (a glue made from animal skin including pig skin) should not be used. However, the Koran also speaks of “law of necessity”, in case the believer does not have a halal to choose from, forcing the use of haram will not be considered a sin. Immunizations are meant to protect life, as “izalat aldharar” (prevention of harm), and “maslahat al ummah” (for the public good). So even if a certain vaccine is related to pigs, it is still possible to apply “forced law when necessary”. Some religions or religious sects may be anti-vaccination. Protestantism does not have a central system, so local churches have very different attitudes on vaccination. Some Protestant priests do not raise the issue of vaccinations in their sermons because they think this is a generally accepted attitude of the whole society. Others leave it to the laity to interpret and choose their attitude towards vaccines. Still others have publicly condemned vaccines, arguing that vaccination is an intervention against God’s will (interfering with Divine Providence). 2. Belief in science and attitudes towards vaccines Key references: Sturgis et al. Trust in science, social consensus and vaccine confidence. Nature Human Behaviour May 17, 2021. This is a study published last week by three authors Patrick Sturgis, Ian Brunton-Smith and Jonathan Jackson from the London School of Economics and Politics (LSE), the University of Surrey (UK) and the University of Sydney Law School (Australia). . https://www.nature.com/articles/s41562-021-01115-7.pdf. The authors analyze data obtained from the Wellcome Global Monitor (Gallup Institute) survey, conducted since 2018 (before the Covid-19 pandemic), about people’s trust in science and the attitude to accept vaccines in Vietnam. 144 countries. The average number of participants in each country was 1000, with China, India and Russia alone being sampled 2000 people from each country. In this poll, the global average result is that more than four-fifths of the population believe in science, the highest in North America, Western Europe, Australia and New Zealand, the lowest in South America, Eastern Europe and Africa. Chau. The percentage of men who believe in science is higher than that of women. Scientific trust is also higher among the educated and high-income population. In countries where the gap between rich and poor is low, there is often high scientific trust. Regarding the attitude of accepting vaccines, about 92% of the global population think that vaccination of children is necessary, 78% think that vaccines are safe, and 84% think that vaccines are effective. This attitude also varies markedly across countries. Again, this is the result of an investigation from 2018, that is, about vaccines in general, not just the vaccine against Co Vi. Next, the authors analyzed the correlation between trust in science and vaccine acceptance attitude. A major part of the results can be illustrated by Figure 1, where countries are divided into five groups according to the assessment of science trust and vaccine acceptance from high to low (left to right). In the highest group, the consensus between scientific belief and vaccine acceptance attitude is highest (blue graph has the steepest slope). This correlation decreases, in the lowest group, the graph is horizontal, which means that there is almost no consensus between scientific beliefs and vaccine acceptance attitudes. Illustration: The relationship between scientific beliefs and vaccine acceptance attitudes. Credit: Nature Human Behaviour 2021. Someone may counter that “I know Mr. A is very rich and Mr. B is highly educated, but neither of them accept vaccines”. Please answer that the above research results are based on the science of statistical probability. That is, the results are only true for the majority, not necessarily for individuals. And statistical probability also tells us that when we deduce from a few particular observations to apply to the majority, the probability of right/wrong can be only 50/50.